UniProt O75787
Renin receptor (O75787)
Renin receptor (UniProt O75787): 14 experimental structures on GenesisL1, 5 ligands bound, 9 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- O75787
- Protein
- Renin receptor
- Experimental structures
- 14
- Predicted models
- 0
- Ligands
- 5
- Pockets
- 9 · 5 records with a druggable one
Structures
14 records of O75787 in the MolNFT archive: 14 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3LBS | Crystal structure of the cytoplasmic tail of (pro)renin receptor as a MBP fusion (Maltose-bound… | x-ray diffraction | A, B | — | — |
| 3LBS | Crystal structure of the cytoplasmic tail of (PRO)RENIN receptor as a mbp fusion (maltose-bound… | x-ray diffraction | A, B | — | — |
| 3LC8 | Crystal structure of the cytoplasmic tail of (pro)renin receptor as a MBP fusion (Maltose-free form) | x-ray diffraction | A, B | — | — |
| 3LC8 | Crystal structure of the cytoplasmic tail of (PRO)RENIN receptor as a mbp fusion (maltose-free form) | x-ray diffraction | A, B | — | — |
| 6WLW | The Vo region of human V-ATPase in state 1 (focused refinement) | electron microscopy | V | NAG, WSS, WJS, CLR, PTY | 4 (best 0.83) |
| 6WLW | The vo region of human V-ATPase in state 1 (focused refinement) | electron microscopy | V | NAG, WSS, WJS, CLR, PTY | — |
| 6WM2 | Human V-ATPase in state 1 with SidK and ADP | electron microscopy | V | NAG, WSS, CLR, WJS, PTY | 2 (best 0.82) |
| 6WM2 | Human V-ATPase in state 1 with sidk and ADP | electron microscopy | V | NAG, WSS, CLR, WJS, PTY | — |
| 6WM3 | Human V-ATPase in state 2 with SidK and ADP | electron microscopy | V | — | 1 (best 0.83) |
| 6WM3 | Human V-ATPase in state 2 with sidk and ADP | electron microscopy | V | — | — |
| 6WM4 | Human V-ATPase in state 3 with SidK and ADP | electron microscopy | V | — | 1 (best 0.82) |
| 6WM4 | Human V-ATPase in state 3 with sidk and ADP | electron microscopy | V | — | — |
| 7U4T | Human V-ATPase in state 2 with SidK and mEAK-7 | electron microscopy | V | — | 1 (best 0.82) |
| O75787 | AlphaFold monomer V2.0 prediction for renin receptor (O75787) | — | — | — |
Ligands
- CLR · Cholesterol · in 4 records
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 4 records
- PTY · Phosphatidylethanolamine · in 4 records
- WJS · (2~{S})-2-$l^{4}-azanyl-3-[[(2~{R})-3-octadecanoyloxy-2-oxidanyl-propoxy]-oxidanyl-oxidanylidene-$l^{6}-phosphanyl]oxy-propanoic acid · in 4 records
- WSS · tri(methyl)-[2-[[(2~{R})-2-[(~{Z})-octadec-9-enoyl]oxy-3-[(~{E})-1-oxidanylideneoctadec-9-enoxy]propoxy]-oxidanyl-phosphoryl]oxyethyl]azanium · in 4 records
Experiment against prediction
- 3LBS chain A against the predicted model P0AEX9: TM-score 0.98, RMSD 0.96 Å
- 3LBS chain B against the predicted model P0AEX9: TM-score 0.97, RMSD 0.99 Å
- 3LC8 chain A against the predicted model P0AEX9: TM-score 0.81, RMSD 3.55 Å
- 3LC8 chain B against the predicted model P0AEX9: TM-score 0.80, RMSD 3.56 Å
Elsewhere
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