UniProt O74859
Aprataxin-like protein (O74859)
Aprataxin-like protein (UniProt O74859), EC 3.-.-.-: 12 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O74859
- Protein
- Aprataxin-like protein
- EC
- 3.-.-.-
- Experimental structures
- 12
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 3 · 1 record with a druggable one
Structures
13 records of O74859 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3SP4 | Crystal structure of aprataxin ortholog Hnt3 from Schizosaccharomyces pombe | x-ray diffraction | A, B | — | — |
| 3SP4 | Crystal structure of aprataxin ortholog HNT3 from schizosaccharomyces pombe | x-ray diffraction | A, B | — | — |
| 3SPD | Crystal structure of aprataxin ortholog Hnt3 in complex with DNA | x-ray diffraction | A, B, C, D | — | — |
| 3SPD | Crystal structure of aprataxin ortholog HNT3 in complex with DNA | x-ray diffraction | A, B, C, D | — | — |
| 3SPL | Crystal structure of aprataxin ortholog Hnt3 in complex with DNA and AMP | x-ray diffraction | A, B, C, D | — | — |
| 3SPL | Crystal structure of aprataxin ortholog HNT3 in complex with DNA and AMP | x-ray diffraction | A, B, C, D | — | — |
| 3SZQ | Structure of an S. pombe APTX/DNA/AMP/Zn complex | x-ray diffraction | A | — | — |
| 3SZQ | Structure of an S. pombe APTX/DNA/AMP/ZN complex | x-ray diffraction | A | — | — |
| 4XBA | Hnt3 | x-ray diffraction | A, B | GMP, ZN, 5GP | 3 (best 0.82) |
| 4XBA | HNT3 | x-ray diffraction | A, B | — | — |
| 4YKL | Hnt3 in complex with DNA and guanosine | x-ray diffraction | B | — | — |
| 4YKL | HNT3 in complex with DNA and guanosine | x-ray diffraction | B | — | — |
| O74859 | AlphaFold monomer V2.0 prediction for aprataxin-like protein (O74859) | predicted | A | — | — |
Ligands
Experiment against prediction
- 3SPL chain A against the predicted model O74859: TM-score 1.00, RMSD 0.36 Å
- 3SPL chain A against the predicted model O74859: TM-score 1.00, RMSD 0.36 Å
- 3SPL chain D against the predicted model O74859: TM-score 1.00, RMSD 0.36 Å
- 3SPL chain D against the predicted model O74859: TM-score 1.00, RMSD 0.36 Å
- 3SPL chain B against the predicted model O74859: TM-score 1.00, RMSD 0.36 Å
- 3SPL chain B against the predicted model O74859: TM-score 1.00, RMSD 0.36 Å
- 3SPD chain B against the predicted model O74859: TM-score 1.00, RMSD 0.36 Å
- 3SPD chain B against the predicted model O74859: TM-score 1.00, RMSD 0.36 Å
- 3SPD chain A against the predicted model O74859: TM-score 1.00, RMSD 0.37 Å
- 3SPD chain A against the predicted model O74859: TM-score 1.00, RMSD 0.37 Å
Elsewhere
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