UniProt O74339
Phosphatidate cytidylyltransferase, mitochondrial (O74339)
Phosphatidate cytidylyltransferase, mitochondrial (UniProt O74339), EC 2.7.7.41: 4 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 26 pockets. Binding sites, druggability and experiment against…
- UniProt
- O74339
- Protein
- Phosphatidate cytidylyltransferase, mitochondrial
- EC
- 2.7.7.41
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 26 · 3 records with a druggable one
Structures
5 records of O74339 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6IG2 | Structure of mitochondrial CDP-DAG synthase Tam41 complexed with CTP, delta 74, F240A | x-ray diffraction | A, B, C, D | CTP | 17 (best 0.80) |
| 6IG2 | Structure of mitochondrial cdp-dag synthase TAM41 complexed with CTP, delta 74, F240A | x-ray diffraction | A, B, C, D | CTP | — |
| 6IG4 | Structure of mitochondrial CDP-DAG synthase Tam41, delta 74 | x-ray diffraction | A, B | 3G0, PT | 6 (best 0.81) |
| 6IG4 | Structure of mitochondrial cdp-dag synthase TAM41, delta 74 | x-ray diffraction | A, B | 3G0, PT | — |
| O74339 | AlphaFold monomer V2.0 prediction for phosphatidate cytidylyltransferase, mitochondrial (O74339) | predicted | A | — | 3 (best 0.80) |
Ligands
Experiment against prediction
- 6IG2 chain B against the predicted model O74339: TM-score 0.91, RMSD 2.01 Å
- 6IG2 chain A against the predicted model O74339: TM-score 0.90, RMSD 2.00 Å
- 6IG2 chain A against the predicted model O74339: TM-score 0.90, RMSD 2.00 Å
- 6IG4 chain B against the predicted model O74339: TM-score 0.90, RMSD 2.35 Å
- 6IG4 chain B against the predicted model O74339: TM-score 0.90, RMSD 2.35 Å
- 6IG2 chain D against the predicted model O74339: TM-score 0.89, RMSD 2.47 Å
- 6IG2 chain C against the predicted model O74339: TM-score 0.89, RMSD 2.47 Å
- 6IG2 chain C against the predicted model O74339: TM-score 0.89, RMSD 2.47 Å
- 6IG4 chain A against the predicted model O74339: TM-score 0.88, RMSD 2.39 Å
- 6IG4 chain A against the predicted model O74339: TM-score 0.88, RMSD 2.39 Å
Elsewhere
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