UniProt O59487
Probable ribosomal RNA small subunit methyltransferase A (O59487)
Probable ribosomal RNA small subunit methyltransferase A (UniProt O59487), EC 2.1.1.182: 11 experimental structures on GenesisL1, 8 ligands bound, 39 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- O59487
- Protein
- Probable ribosomal RNA small subunit methyltransferase A
- EC
- 2.1.1.182
- Experimental structures
- 11
- Predicted models
- 0
- Ligands
- 8
- Pockets
- 39 · 10 records with a druggable one
Structures
11 records of O59487 in the MolNFT archive: 11 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8X41 | Crystal structure of DIMT1 in complex with 5'-methylthioadenosine and adenosine from Pyrococcus… | x-ray diffraction | A, B | MTA, ADN, ZN, CL, SO3, ARG | 8 (best 0.78) |
| 8X44 | Crystal structure of DIMT1 in complex with 5'-methylthioadenosine from Pyrococcus horikoshii (FormI) | x-ray diffraction | A, B | MTA, ZN, SO3, CL | 2 (best 0.84) |
| 8X45 | Crystal structure of DIMT1 in complex with 5'-methylthioadenosine from Pyrococcus horikoshii… | x-ray diffraction | A, B | MTA, ZN, SO3 | 2 (best 0.84) |
| 8X46 | Crystal structure of DIMT1 in complex with adenosylornithine (SFG) from Pyrococcus horikoshii | x-ray diffraction | A, B | SFG, ZN, CL, ARG, SO3 | 2 (best 0.83) |
| 8X47 | Crystal structure of DIMT1 in complex with S-adenosyl-L-homocysteine (SAH) from Pyrococcus… | x-ray diffraction | A | SAH, ZN, SO3, ARG | 3 (best 0.76) |
| 8X4G | Crystal structure of the D117A mutant of DIMT1 from Pyrococcus horikoshii | x-ray diffraction | A, B | — | 2 (best 0.82) |
| 8X4I | Crystal structure of the D117A mutant of DIMT1 in complex with 5'-methylthioadenosine from… | x-ray diffraction | A | MTA, ZN | 4 (best 0.77) |
| 8X4L | Crystal structure of the N132A mutant of DIMT1 from Pyrococcus horikoshii | x-ray diffraction | A, B | ZN, SO3, ARG | 3 (best 0.84) |
| 8X4O | Crystal structure of the Y135A mutant of DIMT1 in complex with 5'-methylthioadenosine from… | x-ray diffraction | A, B | MTA, ZN | 10 (best 0.79) |
| 8X4P | Crystal structure of the Y135A mutant of DIMT1 in complex with adenosylornithine (SFG) from… | x-ray diffraction | A, B | ZN, SFG | 3 (best 0.86) |
| O59487 | AlphaFold monomer V2.0 prediction for probable ribosomal RNA small subunit methyltransferase a… | — | — | — |
Ligands
Elsewhere
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