UniProt O54440
3-oxoacyl-[acyl-carrier-protein] synthase 2 (O54440)
3-oxoacyl-[acyl-carrier-protein] synthase 2 (UniProt O54440), EC 2.3.1.179: 55 experimental structures on GenesisL1, 51 ligands bound, 285 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- O54440
- Protein
- 3-oxoacyl-[acyl-carrier-protein] synthase 2
- EC
- 2.3.1.179
- Experimental structures
- 55
- Predicted models
- 0
- Ligands
- 51
- Pockets
- 285 · 41 records with a druggable one
Structures
55 records of O54440 in the MolNFT archive: 55 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4B7V | Structure of wild type Pseudomonas aeruginosa FabF (KASII) | x-ray diffraction | A, B | — | — |
| 4B7V | Structure of wild type pseudomonas aeruginosa fabf (kasii) | x-ray diffraction | A, B | — | — |
| 4JB6 | Structure of Pseudomonas aeruginosa FabF mutant C164Q | x-ray diffraction | A, B | — | — |
| 4JB6 | Structure of pseudomonas aeruginosa fabf mutant C164Q | x-ray diffraction | A, B | — | — |
| 5SN5 | PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant… | x-ray diffraction | A, B | Q40, PO4 | 7 (best 0.76) |
| 5SN6 | PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant… | x-ray diffraction | A, B | EJQ, PO4 | — |
| 5SN7 | PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant… | x-ray diffraction | A, B | JMM, PO4 | 6 (best 0.80) |
| 5SN8 | PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant… | x-ray diffraction | A, B | K0Y, PO4 | 7 (best 0.76) |
| 5SN9 | PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant… | x-ray diffraction | A, B | NVD, PO4 | 8 (best 0.77) |
| 5SNA | PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant… | x-ray diffraction | A, B | GX4, PO4 | 7 (best 0.82) |
| 5SNB | PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant… | x-ray diffraction | A, B | LWA, PO4 | 7 (best 0.76) |
| 5SNC | PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant… | x-ray diffraction | A, B | K0D, PO4 | — |
| 5SND | PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant… | x-ray diffraction | A, B | Q49, PO4 | 7 (best 0.77) |
| 5SNE | PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant… | x-ray diffraction | A, B | Q4L, PO4 | 6 (best 0.81) |
| 5SNF | PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant… | x-ray diffraction | A, B | UQM, PO4 | 7 (best 0.77) |
| 5SNG | PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant… | x-ray diffraction | A, B | UV7, PO4 | 7 (best 0.77) |
| 5SNH | PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant… | x-ray diffraction | A, B | O1M, PO4 | 5 (best 0.76) |
| 5SNI | PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant… | x-ray diffraction | A, B | UVA, PO4 | 6 (best 0.77) |
| 5SNJ | PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant… | x-ray diffraction | A, B | K2G, PO4 | 6 (best 0.78) |
| 5SNK | PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant… | x-ray diffraction | A, B | GOV, PO4 | 7 (best 0.77) |
| 5SNL | PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant… | x-ray diffraction | A, B | K34, PO4 | 7 (best 0.77) |
| 5SNM | PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant… | x-ray diffraction | A, B | Q4U, PO4 | 7 (best 0.75) |
| 5SNN | PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant… | x-ray diffraction | A, B | NZ1, PO4 | 8 (best 0.76) |
| 5SNO | PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant… | x-ray diffraction | A, B | Q5H, PO4 | 7 (best 0.76) |
| 5SNP | PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant… | x-ray diffraction | A, B | Q5L, PO4 | 8 (best 0.76) |
| 5SNQ | PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant… | x-ray diffraction | A, B | Q5U, PO4 | 7 (best 0.77) |
| 5SNR | PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant… | x-ray diffraction | A, B | LJA, PO4 | 7 (best 0.78) |
| 5SNS | PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant… | x-ray diffraction | A, B | X1J, PO4 | 7 (best 0.77) |
| 5SNT | PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant… | x-ray diffraction | A, B | JFP, PO4 | 8 (best 0.81) |
| 5SNU | PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant… | x-ray diffraction | A, B | JFJ, PO4 | 6 (best 0.78) |
| 5SNV | PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant… | x-ray diffraction | A, B | X0G, PO4 | — |
| 5SNW | PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant… | x-ray diffraction | A, B | NUM, PO4 | 7 (best 0.77) |
| 5SNX | PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant… | x-ray diffraction | A, B | WN4, PO4 | 8 (best 0.77) |
| 5SNY | PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant… | x-ray diffraction | A, B | K04, PO4 | — |
| 5SNZ | PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant… | x-ray diffraction | A, B | K0V, PO4 | 7 (best 0.77) |
| 5SO0 | PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant… | x-ray diffraction | A, B | 6SU, PO4 | 7 (best 0.77) |
| 5SO1 | PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant… | x-ray diffraction | A, B | GX4, PO4 | 8 (best 0.80) |
| 5SO2 | PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant… | x-ray diffraction | A, B | WJD, PO4 | 7 (best 0.76) |
| 5SO3 | PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant… | x-ray diffraction | A, B | Q63, PO4 | — |
| 5SO4 | PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant… | x-ray diffraction | A, B | Q4K, PO4 | 7 (best 0.81) |
| 5SO5 | PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant… | x-ray diffraction | A, B | Q6C, PO4 | 6 (best 0.81) |
| 5SO6 | PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant… | x-ray diffraction | A, B | Q6O, PO4 | — |
| 5SO7 | PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant… | x-ray diffraction | A, B | RZS, PO4 | 7 (best 0.78) |
| 5SO8 | PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant… | x-ray diffraction | A, B | Q6X, PO4 | — |
| 5SO9 | PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant… | x-ray diffraction | A, B | Q76, PO4 | 7 (best 0.77) |
| 5SOA | PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant… | x-ray diffraction | A, B | Q7E, PO4 | 7 (best 0.78) |
| 5SOB | PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant… | x-ray diffraction | A, B | Q7L, PO4 | 7 (best 0.79) |
| 5SOC | PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant… | x-ray diffraction | A, B | ZQA, PO4 | 6 (best 0.78) |
| 5SOD | PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant… | x-ray diffraction | A, B | Q7X, PO4 | 6 (best 0.76) |
| 5SOE | PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant… | x-ray diffraction | A, B | VVP, PO4 | — |
| 5SOF | PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant… | x-ray diffraction | A, B | NUA, PO4 | 8 (best 0.78) |
| 5SOG | PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant… | x-ray diffraction | A, B | S2Y, PO4 | — |
| 5SOH | PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant… | x-ray diffraction | A, B | JGP, PO4 | 7 (best 0.78) |
| 7OC1 | Structure of Pseudomonas aeruginosa FabF mutant C164Q in complex with Platensimycin | x-ray diffraction | A, B | PMN, K | 8 (best 0.78) |
| 7OC1 | Structure of pseudomonas aeruginosa fabf mutant C164Q in complex with platensimycin | x-ray diffraction | A, B | PMN, K | — |
Ligands
- PO4 · Phosphate ion · in 49 records
- GX4 · cyclopropyl-[4-(4-fluorophenyl)piperazin-1-yl]methanone · in 2 records
- K · Potassium ion · in 2 records
- PMN · Platensimycin · in 2 records
- 6SU · methyl 3-(methylsulfonylamino)benzoate · in 1 record
- EJQ · ~{N}-(4-fluorophenyl)-2-pyrrolidin-1-yl-ethanamide · in 1 record
- GOV · (2S)-1-{[(2H-1,3-benzodioxol-5-yl)methyl]amino}propan-2-ol · in 1 record
- JFJ · 1-(3-chlorophenyl)-N-methylmethanamine · in 1 record
- JFP · N-(4-methyl-1,3-thiazol-2-yl)propanamide · in 1 record
- JGP · (azepan-1-yl)(2H-1,3-benzodioxol-5-yl)methanone · in 1 record
- JMM · [4-(cyclopropanecarbonyl)piperazin-1-yl](furan-2-yl) methanone · in 1 record
- K04 · (2S,3S)-3-methyl-N-(1,2,3-thiadiazol-5-yl)tetrahydrofuran-2-carboxamide (non-preferred name) · in 1 record
- K0D · [(2R,5S)-2,5-dimethylmorpholin-4-yl](1,2,5-thiadiazol-3-yl)methanone · in 1 record
- K0V · methyl 1-(tert-butylcarbamoyl)piperidine-4-carboxylate · in 1 record
- K0Y · methyl N-(5-methyl-1,2-oxazole-3-carbonyl)glycinate · in 1 record
- K2G · 5-chloro-2-(propan-2-yl)pyrimidine-4-carboxamide · in 1 record
- K34 · 5-(1,3-thiazol-2-yl)-1H-1,2,4-triazole · in 1 record
- LJA · N-[3-(carbamoylamino)phenyl]acetamide · in 1 record
- LWA · (2~{S})-~{N}-(4-aminocarbonylphenyl)oxolane-2-carboxamide · in 1 record
- NUA · N-(1-ethyl-1H-pyrazol-4-yl)cyclobutanecarboxamide · in 1 record
- NUM · N-[2-(4-hydroxyphenyl)ethyl]pyridine-2-carboxamide · in 1 record
- NVD · N-{[4-(dimethylamino)phenyl]methyl}-4H-1,2,4-triazol-4-amine · in 1 record
- NZ1 · 5-methoxy-1,3-benzothiazol-2-amine · in 1 record
- O1M · 4-(4-fluorophenyl)piperazine-1-carboxamide · in 1 record
- Q40 · 1-(2-phenylethyl)piperidine-4-carboxamide · in 1 record
- Q49 · (3S)-3-(3-fluorophenoxy)-1-methylpyrrolidin-2-one · in 1 record
- Q4K · ethyl (2~{S},3~{R})-3-(5-bromanylpyridin-2-yl)-2-fluoranyl-3-oxidanyl-propanoate · in 1 record
- Q4L · methyl 4-(4-fluorophenyl)piperazine-1-carboxylate · in 1 record
- Q4U · N,N-diethyl-3-methyl-1,2-oxazole-5-carboxamide · in 1 record
- Q5H · 3-acetamido-2-methylbenzoic acid · in 1 record
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.