GL1X · GenesisL1 explorer

Ligand · JMM

JMM · [4-(cyclopropanecarbonyl)piperazin-1-yl](furan-2-yl) methanone

JMM, [4-(cyclopropanecarbonyl)piperazin-1-yl](furan-2-yl) methanone (C13 H16 N2 O3, 248.3 g/mol), in the MolNFT structures on GenesisL1: bound in 11 records (9 PDB entries). Every binding site with its residues within 4.5 Å, the residues…

Component
JMM
Formula
C13 H16 N2 O3
Class
ligand
Structures
11
PDB entries
9

Binding sites

JMM in 11 structures; the first of them:

  • 5QEX · PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with… · JMM A401 · binds ALA189, LEU192, ASN193, PHE196, GLU200, GLU276, GLY277, PHE280 and 1 more
  • 5RWT · INPP5D PanDDA analysis group deposition -- Crystal Structure of the phosphatase and C2… · JMM A901 · binds LEU620, ARG623, PHE632, GLU633, GLU634, GLU635, GLU636
  • 5QEX · Pandda analysis group deposition -- crystal structure of PTP1B in complex with… · JMM A401 · binds ALA189, LEU192, PHE196, GLU276, GLY277, PHE280
  • 5QJ7 · Pandda analysis group deposition of models with modelled events (E.G. bound ligands)… · JMM A303 · binds TRP28, VAL29, ARG51, ASP164, GLY165, ARG44, THR45, TRP46 and 3 more
  • 5QRH · Pandda analysis group deposition -- crystal structure of human brachyury in complex with… · JMM A306 · binds SER89, ILE125, SER129, PRO130, VAL175
  • 5QS7 · Pandda analysis group deposition -- crystal structure of human brachyury G177D variant in… · JMM A301 · binds ARG43, VAL44, GLY45, LEU46, SER49, GLU189
  • 5R4V · Xchem fragment screen -- crystal structure of the bromodomain of the human ATAD2 in… · JMM A1201 · binds VAL1008, PHE1009, GLU1017, VAL1018, TYR1021, TYR1063, ASN1064, ILE1074
  • 5R9U · Pandda analysis group deposition FORM1 MAP kinase P38-alpha -- fragment N13475A in… · JMM A401 · binds TYR35, VAL38, ALA51, LYS53, LEU104, THR106, HIS107, LEU108 and 4 more
  • 5RWT · INPP5D pandda analysis group deposition -- crystal structure of the phosphatase and C2… · JMM A901 · binds ARG623, PHE632, GLU633, GLU634, GLU636
  • 5S9U · Pandda analysis group deposition -- crystal structure of trypanosoma brucei trypanothione… · JMM A508 · binds PHE198, GLY229, PHE230, LEU334, SER364, ALA365, GLY376
  • 5SDJ · Pandda analysis group deposition -- crystal structure of porphyromonas gingivalis in… · JMM A801 · binds ASP317, MET323, ALA444, ASN445, LYS446, TYR448, SER449

Residues it binds most

GLU 11, GLY 9, LEU 11, PHE 7, ARG 6, TRP 4, VAL 7, ALA 6, ASP 6, SER 5 (residue and the binding sites it lines).

Found with

  • DMS · Dimethyl sulfoxide
  • CL · Chloride ion
  • MG · Magnesium ion
  • SO4 · Sulfate ion
  • EDO · 1,2-ethanediol
  • TRS · 2-amino-2-hydroxymethyl-propane-1,3-diol
  • FAD · Flavin-adenine dinucleotide
  • CD · Cadmium ion
  • BR · Bromide ion

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.