UniProt O53872
3-hydroxyacyl-CoA dehydrogenase (O53872)
3-hydroxyacyl-CoA dehydrogenase (UniProt O53872), EC 1.1.1.35: 36 experimental structures on GenesisL1, 21 ligands bound, 293 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- O53872
- Protein
- 3-hydroxyacyl-CoA dehydrogenase
- EC
- 1.1.1.35
- Experimental structures
- 36
- Predicted models
- 0
- Ligands
- 21
- Pockets
- 293 · 17 records with a druggable one
Structures
36 records of O53872 in the MolNFT archive: 36 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4B3H | Crystal structure of Mycobacterium tuberculosis fatty acid beta- oxidation complex | x-ray diffraction | A, B | — | — |
| 4B3H | Crystal structure of mycobacterium tuberculosis fatty acid beta-oxidation complex | x-ray diffraction | A, B | — | — |
| 4B3I | Crystal structure of Mycobacterium tuberculosis fatty acid beta- oxidation complex with CoenzymeA… | x-ray diffraction | A, B | — | — |
| 4B3I | Crystal structure of mycobacterium tuberculosis fatty acid beta-oxidation complex with coenzymea… | x-ray diffraction | A, B | — | — |
| 4B3J | Crystal structure of Mycobacterium tuberculosis fatty acid beta- oxidation complex with CoenzymeA… | x-ray diffraction | A, B | — | — |
| 4B3J | Crystal structure of mycobacterium tuberculosis fatty acid beta-oxidation complex with coenzymea… | x-ray diffraction | A, B | — | — |
| 7O1G | Structure of mycobacterium tuberculosis beta-oxidation trifunctional enzyme alpha-E141A-H462A… | x-ray diffraction | A | SO4 | — |
| 7O1I | Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme alpha-E141A mutant | x-ray diffraction | A | SO4 | 7 (best 0.76) |
| 7O1I | Structure of mycobacterium tuberculosis beta-oxidation trifunctional enzyme alpha-E141A mutant | x-ray diffraction | A | SO4 | — |
| 7O1J | Structure of mycobacterium tuberculosis beta-oxidation trifunctional enzyme beta-C92A mutant | x-ray diffraction | A | SO4 | — |
| 7O1K | Structure of mycobacterium tuberculosis beta-oxidation trifunctional enzyme alpha-E141A, beta-C92A… | x-ray diffraction | A, B | SO4 | — |
| 7O1L | Structure of mycobacterium tuberculosis beta-oxidation trifunctional enzyme alpha-H462A mutant | x-ray diffraction | A | SO4 | — |
| 7O1M | Structure of mycobacterium tuberculosis beta-oxidation trifunctional enzyme alpha-H462A, beta-C92A… | x-ray diffraction | A | SO4 | — |
| 7O4Q | Structure of mycobacterium tuberculosis beta-oxidation trifunctional enzyme in space group C2221… | x-ray diffraction | B | SO4 | — |
| 7O4R | Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme with Coenzyme A bound… | x-ray diffraction | A, B | SO4, COA | 17 (best 0.83) |
| 7O4R | Structure of mycobacterium tuberculosis beta-oxidation trifunctional enzyme with coenzyme a bound… | x-ray diffraction | A, B | SO4, COA | — |
| 7O4S | Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme with Coenzyme A bound… | x-ray diffraction | A, B | SO4, COA, PAP, ADP | — |
| 7O4S | Structure of mycobacterium tuberculosis beta-oxidation trifunctional enzyme with coenzyme a bound… | x-ray diffraction | A, B | SO4, COA, PAP, ADP | — |
| 7O4T | Structure of mycobacterium tuberculosis beta-oxidation trifunctional enzyme with coenzyme a bound… | x-ray diffraction | A, B | COA, PAP, SO4 | — |
| 7O4U | Structure of the alpha subunit of mycobacterium tuberculosis beta- oxidation trifunctional enzyme… | x-ray diffraction | A, B | NAD | — |
| 7O4V | Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with… | x-ray diffraction | B, A | NAD, SO4 | 18 (best 0.80) |
| 7O4V | Structure of mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with… | x-ray diffraction | B, A | NAD, SO4 | — |
| 8OPV | Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with… | x-ray diffraction | A, B | SO4, STL | 19 (best 0.76) |
| 8OPW | Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with… | x-ray diffraction | A, B | SO4, CFF | 19 (best 0.79) |
| 8OPX | Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with… | x-ray diffraction | B, A | GLC, SO4 | 15 (best 0.81) |
| 8OPY | Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with… | x-ray diffraction | A, B | SO4 | 19 (best 0.78) |
| 8OQL | Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with… | x-ray diffraction | A, B | SO4, A9J | 16 (best 0.78) |
| 8OQN | Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with… | x-ray diffraction | A, B | SO4, W3U | 20 (best 0.80) |
| 8OQP | Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with… | x-ray diffraction | A, B | SO4, VXZ | 19 (best 0.82) |
| 8OQQ | Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with… | x-ray diffraction | A, B | SO4, VWE | 17 (best 0.78) |
| 8OQR | Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with… | x-ray diffraction | A, B | SO4, VWT | 19 (best 0.81) |
| 8OQS | Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with… | x-ray diffraction | A, B | SO4, VWZ | 20 (best 0.81) |
| 8OQT | Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with… | x-ray diffraction | B, A | SO4, VXC | 19 (best 0.80) |
| 8OQU | Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with… | x-ray diffraction | A, B | SO4, VXN | 15 (best 0.81) |
| 8OQV | Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with… | x-ray diffraction | A, B | SO4, VWI | 19 (best 0.82) |
| 8PF8 | Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with… | x-ray diffraction | A, B | SO4, YMK, YLZ, YLN, JXL | 15 (best 0.84) |
Ligands
- SO4 · Sulfate ion · in 29 records
- COA · Coenzyme A · in 5 records
- NAD · Nicotinamide-adenine-dinucleotide · in 3 records
- PAP · 3'-phosphate-adenosine-5'-diphosphate · in 3 records
- ADP · Adenosine-5'-diphosphate · in 2 records
- A9J · Hexafluorophosphate anion · in 1 record
- CFF · Caffeine · in 1 record
- GLC · alpha-D-glucopyranose · in 1 record
- JXL · [2-methyl-5-(trifluoromethyl)pyrazol-3-yl]boronic acid · in 1 record
- STL · Resveratrol · in 1 record
- VWE · 2-fluoranyl-5-sulfo-benzoic acid · in 1 record
- VWI · 4-nitrobenzenesulfonic acid · in 1 record
- VWT · 4-cyanobenzenesulfonic acid · in 1 record
- VWZ · 4-phenylbenzenesulfonic acid · in 1 record
- VXC · 4-bromanylbenzenesulfonic acid · in 1 record
- VXN · 4-chloranylbenzenesulfonic acid · in 1 record
- VXZ · 2-azanyl-5-sulfo-benzoic acid · in 1 record
- W3U · 1-benzyl-1H-pyrazole-4-carboxylic acid · in 1 record
- YLN · bis[2-methyl-5-(trifluoromethyl)pyrazol-3-yl]-bis(oxidanyl)boranuide · in 1 record
- YLZ · [(2~{R})-2,3-bis(oxidanyl)propoxy]-[2-methyl-5-(trifluoromethyl)pyrazol-3-yl]borinic acid · in 1 record
- YMK · (2~{R})-3-bis[2-methyl-5-(trifluoromethyl)pyrazol-3-yl]boranyloxypropane-1,2-diol · in 1 record
Elsewhere
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