UniProt O53507
(2E,6E)-farnesyl diphosphate synthase (O53507)
(2E,6E)-farnesyl diphosphate synthase (UniProt O53507), EC 2.5.1.1, 2.5.1.10: 3 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 11 pockets. Binding sites, druggability and experiment against…
- UniProt
- O53507
- Protein
- (2E,6E)-farnesyl diphosphate synthase
- EC
- 2.5.1.1, 2.5.1.10
- Experimental structures
- 3
- Predicted models
- 1
- Ligands
- 5
- Pockets
- 11 · 3 records with a druggable one
Structures
4 records of O53507 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8F8F | The structure of Rv2173 from M. tuberculosis (APO form) | x-ray diffraction | A, B | MG | 7 (best 0.76) |
| 8F8K | The structure of Rv2173 from M. tuberculosis with IPP bound | x-ray diffraction | A | IPE, CA, CL | 2 (best 0.77) |
| 8F8L | The structure of Rv2173 from M. tuberculosis with DMAP bound | x-ray diffraction | A | DMA, CA | 2 (best 0.75) |
| O53507 | AlphaFold monomer V2.0 prediction for (2E,6E)-farnesyl diphosphate synthase (O53507) | predicted | A | — | — |
Ligands
Experiment against prediction
- 8F8K chain A against the predicted model O53507: TM-score 0.97, RMSD 1.13 Å
- 8F8F chain A against the predicted model O53507: TM-score 0.97, RMSD 1.13 Å
- 8F8F chain B against the predicted model O53507: TM-score 0.97, RMSD 1.19 Å
- 8F8L chain A against the predicted model O53507: TM-score 0.97, RMSD 1.25 Å
Elsewhere
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