UniProt O43837
O43837
O43837 (UniProt O43837): 8 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O43837
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 4
Structures
9 records of O43837 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6KDE | Crystal structure of the alpha beta heterodimer of human IDH3 in complex with Ca(2+) | x-ray diffraction | B, D | CA | — |
| 6KDE | Crystal structure of the alpha beta heterodimer of human IDH3 in complex with CA(2+) | x-ray diffraction | B, D | CA | — |
| 6KDF | Crystal structure of the alpha beta heterodimer of human IDH3 in APO form. | x-ray diffraction | C, D, F, H, J, L, N, P | — | — |
| 6KDF | Crystal structure of the alpha beta heterodimer of human IDH3 in apo form. | x-ray diffraction | C, D, F, H, J, L, N, P | — | — |
| 6KDY | Crystal structure of the alpha bata heterodimer of human IDH3 in complex with NAD. | x-ray diffraction | B, D, F, H | NAD, PE7 | — |
| 6KDY | Crystal structure of the alpha bata heterodimer of human IDH3 in complex with NAD. | x-ray diffraction | B, D, F, H | NAD, PE7 | — |
| 6KE3 | Crystal structure of the alpha bata heterodimer of human IDH3 in complex with NADH | x-ray diffraction | B, D, F, H | NAI | — |
| 7CE3 | Crystal structure of human IDH3 holoenzyme in apo form. | x-ray diffraction | D | — | — |
| O43837 | AlphaFold monomer V2.0 prediction for isocitrate dehydrogenase [NAD] subunit beta, mitochondrial… | predicted | A | — | — |
Ligands
Experiment against prediction
- 6KDF chain J against the predicted model O43837: TM-score 0.98, RMSD 1.06 Å
- 6KDF chain J against the predicted model O43837: TM-score 0.98, RMSD 1.06 Å
- 6KDF chain F against the predicted model O43837: TM-score 0.97, RMSD 1.06 Å
- 6KDF chain F against the predicted model O43837: TM-score 0.97, RMSD 1.06 Å
- 6KDF chain L against the predicted model O43837: TM-score 0.97, RMSD 1.14 Å
- 6KDF chain L against the predicted model O43837: TM-score 0.97, RMSD 1.14 Å
- 6KDE chain B against the predicted model O43837: TM-score 0.97, RMSD 1.10 Å
- 6KDE chain B against the predicted model O43837: TM-score 0.97, RMSD 1.10 Å
- 6KDF chain N against the predicted model O43837: TM-score 0.97, RMSD 1.21 Å
- 6KDF chain N against the predicted model O43837: TM-score 0.97, RMSD 1.21 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.