UniProt O43070
DNA repair and telomere maintenance protein NBS1 (O43070)
DNA repair and telomere maintenance protein NBS1 (UniProt O43070): 14 experimental structures and 1 predicted model on GenesisL1, 5 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O43070
- Protein
- DNA repair and telomere maintenance protein NBS1
- Experimental structures
- 14
- Predicted models
- 1
- Pockets
- 5 · 1 record with a druggable one
Structures
15 records of O43070 in the MolNFT archive: 14 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3HUE | Structure of the S. pombe Nbs1 FHA-BRCT1-BRCT2 domains | x-ray diffraction | A | — | — |
| 3HUE | Structure of the S. pombe NBS1 fha-BRCT1-BRCT2 domains | x-ray diffraction | A | — | — |
| 3HUF | Structure of the S. pombe Nbs1-Ctp1 complex | x-ray diffraction | A, B, C | — | — |
| 3HUF | Structure of the S. pombe NBS1-CTP1 complex | x-ray diffraction | A, B, C | — | — |
| 3I0M | Structure of the S. pombe Nbs1 FHA/BRCT-repeat domain | x-ray diffraction | A | — | — |
| 3I0M | Structure of the S. pombe NBS1 FHA/BRCT-repeat domain | x-ray diffraction | A | — | — |
| 3I0N | Structure of the S. pombe Nbs1 FHA/BRCT-repeat domain | x-ray diffraction | A, B | — | — |
| 3I0N | Structure of the S. pombe NBS1 FHA/BRCT-repeat domain | x-ray diffraction | A, B | — | — |
| 4FBK | Crystal structure of a covalently fused Nbs1-Mre11 complex with one manganese ion per active site | x-ray diffraction | A, B | — | — |
| 4FBK | Crystal structure of a covalently fused NBS1-MRE11 complex with one manganese ion per active site | x-ray diffraction | A, B | — | — |
| 4FBQ | Crystal structure of a covalently fused Nbs1-Mre11 complex with two manganese ions per active site | x-ray diffraction | A, B | — | — |
| 4FBQ | Crystal structure of a covalently fused NBS1-MRE11 complex with two manganese ions per active site | x-ray diffraction | A, B | — | — |
| 4FBW | Crystal structure of an unfused Mre11-Nbs1 complex with two manganese ions per active site | x-ray diffraction | C, D | — | — |
| 4FBW | Crystal structure of an unfused MRE11-NBS1 complex with two manganese ions per active site | x-ray diffraction | C, D | — | — |
| O43070 | AlphaFold monomer V2.0 prediction for DNA repair and telomere maintenance protein NBS1 (O43070) | predicted | A | — | 5 (best 0.58) |
Experiment against prediction
- 3HUE chain A against the predicted model O43070: TM-score 0.97, RMSD 1.20 Å
- 3HUE chain A against the predicted model O43070: TM-score 0.97, RMSD 1.20 Å
- 3I0N chain A against the predicted model O43070: TM-score 0.96, RMSD 1.38 Å
- 3I0N chain A against the predicted model O43070: TM-score 0.96, RMSD 1.38 Å
- 3I0N chain B against the predicted model O43070: TM-score 0.96, RMSD 1.41 Å
- 3I0N chain B against the predicted model O43070: TM-score 0.96, RMSD 1.41 Å
- 3I0M chain A against the predicted model O43070: TM-score 0.95, RMSD 1.55 Å
- 3I0M chain A against the predicted model O43070: TM-score 0.95, RMSD 1.55 Å
- 3HUF chain A against the predicted model O43070: TM-score 0.94, RMSD 1.47 Å
- 3HUF chain A against the predicted model O43070: TM-score 0.94, RMSD 1.47 Å
Elsewhere
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