MolNFT v1 · #66578 · protein
Structure of the S. pombe NBS1 fha-BRCT1-BRCT2 domains
3HUE · DNA repair and telomere maintenance protein NBS1: “Structure of the S. pombe NBS1 fha-BRCT1-BRCT2 domains”. X-ray diffraction, 1 pocket (best druggability 0.40). MolNFT v1 #66578 on GenesisL1: 3D structure, binding sites and pockets…
- PDB
- 3HUE
- Type
- protein
- Length
- 307 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- DNA repair and telomere maintenance protein NBS1
- UniProt
- O43070
- Pockets
- 1 · best druggability 0.40
Structure
x-ray diffraction · 1 distinct chain · 32% helix, 24% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA repair and telomere maintenance protein NBS1 | protein | 307 | 32% helix, 24% strand | O43070 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 62 | 0.40 | 0.80 | 15 | empty |
Modifications
Observed in the structure: 8 modified (engineered).
Compared structures
- 3HUE · Structure of the S. pombe Nbs1 FHA-BRCT1-BRCT2 domains · the same entry in another collection · chain A against A, TM-score 1.00
- O43070 · AlphaFold monomer V2.0 prediction for DNA repair and telomere maintenance protein NBS1… · a predicted model of the same protein · chain A against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O43070
- Elsewhere: RCSB PDB 3HUE · PDBe 3HUE · UniProt O43070
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.