UniProt O34632
Sirohydrochlorin ferrochelatase (O34632)
Sirohydrochlorin ferrochelatase (UniProt O34632), EC 4.99.1.4: 7 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 11 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- O34632
- Protein
- Sirohydrochlorin ferrochelatase
- EC
- 4.99.1.4
- Experimental structures
- 7
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 11 · 3 records with a druggable one
Structures
8 records of O34632 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5ZT7 | Sirb from bacillus subtilis with CO2+ | x-ray diffraction | A, B | CO | — |
| 5ZT8 | SirB from Bacillus subtilis | x-ray diffraction | A, B | — | 5 (best 0.73) |
| 5ZT8 | Sirb from bacillus subtilis | x-ray diffraction | A, B | — | — |
| 5ZT9 | SirB from Bacillus subtilis with Ni2+ | x-ray diffraction | A, B | NI | — |
| 5ZT9 | Sirb from bacillus subtilis with NI2+ | x-ray diffraction | A, B | NI | — |
| 5ZTA | SirB from Bacillus subtilis with Fe3+ | x-ray diffraction | A, B | FE | 5 (best 0.73) |
| 5ZTA | Sirb from bacillus subtilis with FE3+ | x-ray diffraction | A, B | FE | — |
| O34632 | AlphaFold monomer V2.0 prediction for sirohydrochlorin ferrochelatase (O34632) | predicted | A | — | 1 (best 0.72) |
Ligands
Experiment against prediction
- 5ZT7 chain A against the predicted model O34632: TM-score 0.99, RMSD 0.56 Å
- 5ZT9 chain B against the predicted model O34632: TM-score 0.99, RMSD 0.66 Å
- 5ZT9 chain B against the predicted model O34632: TM-score 0.99, RMSD 0.66 Å
- 5ZTA chain B against the predicted model O34632: TM-score 0.98, RMSD 0.75 Å
- 5ZTA chain B against the predicted model O34632: TM-score 0.98, RMSD 0.75 Å
- 5ZTA chain A against the predicted model O34632: TM-score 0.98, RMSD 0.81 Å
- 5ZTA chain A against the predicted model O34632: TM-score 0.98, RMSD 0.81 Å
- 5ZT8 chain A against the predicted model O34632: TM-score 0.98, RMSD 0.88 Å
- 5ZT8 chain A against the predicted model O34632: TM-score 0.98, RMSD 0.88 Å
- 5ZT8 chain B against the predicted model O34632: TM-score 0.98, RMSD 0.75 Å
Elsewhere
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