UniProt O32323
Homospermidine synthase (O32323)
Homospermidine synthase (UniProt O32323), EC 2.5.1.44: 26 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 26 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O32323
- Protein
- Homospermidine synthase
- EC
- 2.5.1.44
- Experimental structures
- 26
- Predicted models
- 1
- Ligands
- 5
- Pockets
- 26 · 3 records with a druggable one
Structures
27 records of O32323 in the MolNFT archive: 26 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4PLP | Crystal Structure of the Homospermidine Synthase (HSS) from Blastochloris viridis in Complex with… | x-ray diffraction | A, B | — | — |
| 4PLP | Crystal structure of the homospermidine synthase (hss) from blastochloris viridis in complex with… | x-ray diffraction | A, B | — | — |
| 4TVB | Crystal Structure of the Homospermidine Synthase (HSS) from Blastochloris viridis in Complex with… | x-ray diffraction | A, B | — | — |
| 4TVB | Crystal structure of the homospermidine synthase (hss) from blastochloris viridis in complex with… | x-ray diffraction | A, B | — | — |
| 4XQ9 | Crystal Structure of the Homospermidine Synthase (HSS) from Blastochloris viridis in Complex with… | x-ray diffraction | A, B | NAD | 7 (best 0.82) |
| 4XQ9 | Crystal structure of the homospermidine synthase (hss) from blastochloris viridis in complex with… | x-ray diffraction | A, B | — | — |
| 4XQC | Crystal Structure of the Homospermidine Synthase (HSS) from Blastochloris viridis in Complex with… | x-ray diffraction | A, B | — | — |
| 4XQC | Crystal structure of the homospermidine synthase (hss) from blastochloris viridis in complex with… | x-ray diffraction | A, B | — | — |
| 4XQE | Crystal Structure of the Homospermidine Synthase (HSS) variant H296S from Blastochloris viridis in… | x-ray diffraction | A, B | — | — |
| 4XQE | Crystal structure of the homospermidine synthase (hss) variant H296S from blastochloris viridis in… | x-ray diffraction | A, B | — | — |
| 4XQG | Crystal Structure of the Homospermidine Synthase (HSS) variant E237Q from Blastochloris viridis in… | x-ray diffraction | A, B | — | — |
| 4XQG | Crystal structure of the homospermidine synthase (hss) variant E237Q from blastochloris viridis in… | x-ray diffraction | A, B | — | — |
| 4XR4 | Crystal Structure of the Homospermidine Synthase (HSS) from Blastochloris viridis in Complex with… | x-ray diffraction | A, B | — | — |
| 4XR4 | Crystal structure of the homospermidine synthase (hss) from blastochloris viridis in complex with… | x-ray diffraction | A, B | — | — |
| 4XRG | Crystal Structure of the Homospermidine Synthase (HSS) variant H296S from Blastochloris viridis in… | x-ray diffraction | A, B | — | — |
| 4XRG | Crystal structure of the homospermidine synthase (hss) variant H296S from blastochloris viridis in… | x-ray diffraction | A, B | — | — |
| 6S3X | Crystal structure of the homospermidine synthase (hss) variant E210Q from blastochloris viridis in… | x-ray diffraction | A, B | SO4, AG2, NAD | — |
| 6S49 | Crystal structure of the homospermidine synthase (hss) variant E210A from blastochloris viridis in… | x-ray diffraction | A, B | AG2, SO4, NAD | — |
| 6S4D | Crystal Structure of the Homospermidine Synthase (HSS) variant W229F from Blastochloris viridis in… | x-ray diffraction | A, B | NAD, 1PS | 9 (best 0.80) |
| 6S4D | Crystal structure of the homospermidine synthase (hss) variant W229F from blastochloris viridis in… | x-ray diffraction | A, B | NAD, 1PS | — |
| 6S65 | Crystal Structure of the Homospermidine Synthase (HSS) variant N135F from Blastochloris viridis in… | x-ray diffraction | A, B | NAD | 10 (best 0.78) |
| 6S65 | Crystal structure of the homospermidine synthase (hss) variant N135F from blastochloris viridis in… | x-ray diffraction | A, B | NAD | — |
| 6S6G | Crystal structure of the homospermidine synthase (hss) variant E117Q from blastochloris viridis in… | x-ray diffraction | A, B | NAD, SO4, 1PS | — |
| 6S72 | Crystal structure of the homospermidine synthase (hss) variant W229A from blastochloris viridis in… | x-ray diffraction | A, B | NAD, PUT | — |
| 6SEP | Crystal Structure of the Homospermidine Synthase (HSS) variant W229E from Blastochloris viridis in… | x-ray diffraction | A, B | NAD | — |
| 6SEP | Crystal structure of the homospermidine synthase (hss) variant W229E from blastochloris viridis in… | x-ray diffraction | A, B | NAD | — |
| O32323 | AlphaFold monomer V2.0 prediction for homospermidine synthase (O32323) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6S49 chain A against the predicted model O32323: TM-score 1.00, RMSD 0.21 Å
- 6S3X chain A against the predicted model O32323: TM-score 1.00, RMSD 0.21 Å
- 4XQ9 chain B against the predicted model O32323: TM-score 1.00, RMSD 0.22 Å
- 4XQG chain B against the predicted model O32323: TM-score 1.00, RMSD 0.24 Å
- 4XQG chain B against the predicted model O32323: TM-score 1.00, RMSD 0.24 Å
- 6S72 chain A against the predicted model O32323: TM-score 1.00, RMSD 0.28 Å
- 6S4D chain A against the predicted model O32323: TM-score 1.00, RMSD 0.28 Å
- 6S4D chain A against the predicted model O32323: TM-score 1.00, RMSD 0.28 Å
- 6SEP chain A against the predicted model O32323: TM-score 1.00, RMSD 0.28 Å
- 6SEP chain A against the predicted model O32323: TM-score 1.00, RMSD 0.28 Å
Elsewhere
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