UniProt O22476
Protein BRASSINOSTEROID INSENSITIVE 1 (O22476)
Protein BRASSINOSTEROID INSENSITIVE 1 (UniProt O22476), EC 2.7.10.1, 2.7.11.1: 29 experimental structures and 1 predicted model on GenesisL1, 7 ligands bound, 11 pockets. Binding sites, druggability and experiment against…
- UniProt
- O22476
- Protein
- Protein BRASSINOSTEROID INSENSITIVE 1
- EC
- 2.7.10.1, 2.7.11.1
- Experimental structures
- 29
- Predicted models
- 1
- Ligands
- 7
- Pockets
- 11 · 5 records with a druggable one
Structures
30 records of O22476 in the MolNFT archive: 29 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3RGX | Structural insight into brassinosteroid perception by BRI1 | x-ray diffraction | A | — | — |
| 3RGX | Structural insight into brassinosteroid perception by BRI1 | x-ray diffraction | A | — | — |
| 3RGZ | Structural insight into brassinosteroid perception by BRI1 | x-ray diffraction | A | — | — |
| 3RGZ | Structural insight into brassinosteroid perception by BRI1 | x-ray diffraction | A | — | — |
| 3RIZ | Crystal structure of the plant steroid receptor BRI1 ectodomain | x-ray diffraction | A | — | — |
| 3RIZ | Crystal structure of the plant steroid receptor BRI1 ectodomain | x-ray diffraction | A | — | — |
| 3RJ0 | Plant steroid receptor BRI1 ectodomain in complex with brassinolide | x-ray diffraction | A | — | — |
| 3RJ0 | Plant steroid receptor BRI1 ectodomain in complex with brassinolide | x-ray diffraction | A | — | — |
| 4LSA | Crystal structure of BRI1 sud1 (Gly643Glu) bound to brassinolide | x-ray diffraction | A | — | — |
| 4LSA | Crystal structure of BRI1 SUD1 (GLY643GLU) bound to brassinolide | x-ray diffraction | A | — | — |
| 4LSX | Plant steroid receptor ectodomain bound to brassinolide and SERK1 co- receptor ectodomain | x-ray diffraction | A, B | — | — |
| 4M7E | Structural insight into BL-induced activation of the BRI1-BAK1 complex | x-ray diffraction | A, B | — | — |
| 4M7E | Structural insight into bl-induced activation of the BRI1-BAK1 complex | x-ray diffraction | A, B | — | — |
| 4OH4 | Crystal structure of BRI1 in complex with BKI1 | x-ray diffraction | A, B | — | — |
| 4OH4 | Crystal structure of BRI1 in complex with BKI1 | x-ray diffraction | A, B | — | — |
| 4Q5J | Crystal structure of SeMet derivative BRI1 in complex with BKI1 | x-ray diffraction | A, B | — | — |
| 4Q5J | Crystal structure of semet derivative BRI1 in complex with BKI1 | x-ray diffraction | A, B | — | — |
| 5LPB | Crystal structure of the BRI1 kinase domain (865-1160) in complex with ADP from Arabidopsis thaliana | x-ray diffraction | A | ADP | 2 (best 0.61) |
| 5LPB | Crystal structure of the BRI1 kinase domain (865-1160) in complex with ADP from arabidopsis thaliana | x-ray diffraction | A | ADP | — |
| 5LPV | Crystal structure of the BRI1 kinase domain (865-1160) in complex with AMPPNP and Mn from… | x-ray diffraction | A | ANP, MN | 2 (best 0.60) |
| 5LPV | Crystal structure of the BRI1 kinase domain (865-1160) in complex with amppnp and mn from… | x-ray diffraction | A | ANP, MN | — |
| 5LPW | Crystal structure of the apo-BRI1 kinase domain (865-1160) | x-ray diffraction | A | — | — |
| 5LPW | Crystal structure of the apo-BRI1 kinase domain (865-1160) | x-ray diffraction | A | — | — |
| 5LPY | Crystal structure of the BRI1 kinase domain (865-1160) in complex with ATP from Arabidopsis thaliana | x-ray diffraction | A | ATP | 2 (best 0.60) |
| 5LPY | Crystal structure of the BRI1 kinase domain (865-1160) in complex with ATP from arabidopsis thaliana | x-ray diffraction | A | ATP | — |
| 5LPZ | Crystal structure of the BRI1 kinase domain (865-1196) in complex with ADP from Arabidopsis thaliana | x-ray diffraction | A | ADP | 1 (best 0.61) |
| 5LPZ | Crystal structure of the BRI1 kinase domain (865-1196) in complex with ADP from arabidopsis thaliana | x-ray diffraction | A | ADP | — |
| 6FIF | Crystal structure of the BRI1 Gly644-Asp (bri1-6) mutant from Arabidopsis thaliana. | x-ray diffraction | A | NAG, FUC, BMA | 4 (best 0.58) |
| 6FIF | Crystal structure of the BRI1 GLY644-asp (BRI1-6) mutant from arabidopsis thaliana. | x-ray diffraction | A | NAG, BMA | — |
| O22476 | AlphaFold monomer V2.0 prediction for protein brassinosteroid insensitive 1 (O22476) | predicted | A | — | — |
Ligands
- ADP · Adenosine-5'-diphosphate · in 4 records
- ANP · Phosphoaminophosphonic acid-adenylate ester · in 2 records
- ATP · Adenosine-5'-triphosphate · in 2 records
- BMA · beta-D-mannopyranose · in 2 records
- MN · Manganese (II) ion · in 2 records
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 2 records
- FUC · alpha-L-fucopyranose · in 1 record
Experiment against prediction
- 3RGZ chain A against the predicted model O22476: TM-score 0.99, RMSD 0.78 Å
- 3RGZ chain A against the predicted model O22476: TM-score 0.99, RMSD 0.78 Å
- 3RIZ chain A against the predicted model O22476: TM-score 0.99, RMSD 0.76 Å
- 3RIZ chain A against the predicted model O22476: TM-score 0.99, RMSD 0.76 Å
- 3RJ0 chain A against the predicted model O22476: TM-score 0.99, RMSD 0.82 Å
- 3RJ0 chain A against the predicted model O22476: TM-score 0.99, RMSD 0.82 Å
- 3RGX chain A against the predicted model O22476: TM-score 0.99, RMSD 0.88 Å
- 3RGX chain A against the predicted model O22476: TM-score 0.99, RMSD 0.88 Å
- 6FIF chain A against the predicted model O22476: TM-score 0.99, RMSD 0.94 Å
- 6FIF chain A against the predicted model O22476: TM-score 0.99, RMSD 0.94 Å
Elsewhere
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