MolNFT v1 · #126007 · protein
Crystal structure of the BRI1 kinase domain (865-1160) in complex with ATP from arabidopsis thaliana
5LPY · Protein brassinosteroid insensitive 1: “Crystal structure of the BRI1 kinase domain (865-1160) in complex with ATP from arabidopsis thaliana”. X-ray diffraction, 1 ligand (ATP), 2 pockets (best druggability 0.60). MolNFT v1 #126007…
- PDB
- 5LPY
- Type
- protein
- Length
- 286 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Protein brassinosteroid insensitive 1
- EC
- 2.7.10.1, 2.7.11.1
- UniProt
- O22476
- Ligands
- ATP
- Pockets
- 2 · best druggability 0.60
Structure
x-ray diffraction · 1 distinct chain · 43% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Protein brassinosteroid insensitive 1 (EC 2.7.10.1, 2.7.11.1) | protein | 286 | 43% helix, 19% strand | O22476 |
Ligands and binding sites
- ATP · Adenosine-5'-triphosphate · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 266 | 0.60 | 0.79 | 33 | ATP |
| 2 | 79 | 0.34 | 0.75 | 22 | empty |
Modifications
Observed in the structure: 4 modified (phosphorylation).
Compared structures
- 5LPY · Crystal structure of the BRI1 kinase domain (865-1160) in complex with ATP from… · the same entry in another collection · chain A against A, TM-score 1.00
- O22476 · AlphaFold monomer V2.0 prediction for protein brassinosteroid insensitive 1 (O22476) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O22476
- Elsewhere: RCSB PDB 5LPY · PDBe 5LPY · UniProt O22476
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