MolNFT v1 · #126005 · protein
Crystal structure of the apo-BRI1 kinase domain (865-1160)
5LPW · Protein brassinosteroid insensitive 1: “Crystal structure of the apo-BRI1 kinase domain (865-1160)”. X-ray diffraction, 2 pockets (best druggability 0.59). MolNFT v1 #126005 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 5LPW
- Type
- protein
- Length
- 284 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Protein brassinosteroid insensitive 1
- EC
- 2.7.10.1, 2.7.11.1
- UniProt
- O22476
- Pockets
- 2 · best druggability 0.59
Structure
x-ray diffraction · 1 distinct chain · 41% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Protein brassinosteroid insensitive 1 (EC 2.7.10.1, 2.7.11.1) | protein | 284 | 41% helix, 17% strand | O22476 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 251 | 0.59 | 0.79 | 26 | empty |
| 2 | 90 | 0.34 | 0.74 | 24 | empty |
Modifications
Observed in the structure: 4 modified (phosphorylation).
Compared structures
- 5LPW · Crystal structure of the apo-BRI1 kinase domain (865-1160) · the same entry in another collection · chain A against A, TM-score 1.00
- O22476 · AlphaFold monomer V2.0 prediction for protein brassinosteroid insensitive 1 (O22476) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O22476
- Elsewhere: RCSB PDB 5LPW · PDBe 5LPW · UniProt O22476
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