UniProt O15540
Fatty acid-binding protein, brain (O15540)
Fatty acid-binding protein, brain (UniProt O15540): 13 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 5 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O15540
- Protein
- Fatty acid-binding protein, brain
- Experimental structures
- 13
- Predicted models
- 1
- Ligands
- 5
- Pockets
- 5 · 3 records with a druggable one
Structures
14 records of O15540 in the MolNFT archive: 13 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1FDQ | Crystal structure of human brain fatty acid binding protein | x-ray diffraction | A, B | — | — |
| 1FDQ | Crystal structure of human brain fatty acid binding protein | x-ray diffraction | A, B | — | — |
| 1FE3 | Crystal structure of human brain fatty acid binding protein oleic acid | x-ray diffraction | A | — | — |
| 1FE3 | Crystal structure of human brain fatty acid binding protein oleic acid | x-ray diffraction | A | — | — |
| 1JJX | Solution Structure of Recombinant Human Brain-type Fatty acid Binding Protein | solution nmr | A | — | — |
| 1JJX | Solution structure of recombinant human brain-type fatty acid binding protein | solution nmr | A | — | — |
| 5URA | Enantiomer-specific binding of the potent antinociceptive agent sbfi- 26 to anandamide transporters… | x-ray diffraction | A, B, C, D | 8KS, SO4 | — |
| 6L9O | Crystal structure of FABP7 apo | x-ray diffraction | A | — | — |
| 6L9O | Crystal structure of FABP7 apo | x-ray diffraction | A | — | — |
| 7E25 | Crystal structure of human FABP7 complexed with palmitic acid | x-ray diffraction | A | PLM, SO4 | 1 (best 0.86) |
| 7E25 | Crystal structure of human FABP7 complexed with palmitic acid | x-ray diffraction | A | PLM, SO4 | — |
| 8IVF | FABP7 complexed with 25-HC | x-ray diffraction | B, A | HC3 | 3 (best 0.85) |
| 8IVL | FABP7 complexed with Cholesterol | x-ray diffraction | A | CLR | 1 (best 0.85) |
| O15540 | AlphaFold monomer V2.0 prediction for fatty acid-binding protein, brain (O15540) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6L9O chain A against the predicted model O15540: TM-score 0.99, RMSD 0.45 Å
- 6L9O chain A against the predicted model O15540: TM-score 0.99, RMSD 0.45 Å
- 8IVF chain A against the predicted model O15540: TM-score 0.99, RMSD 0.46 Å
- 7E25 chain A against the predicted model O15540: TM-score 0.94, RMSD 0.47 Å
- 7E25 chain A against the predicted model O15540: TM-score 0.94, RMSD 0.47 Å
- 1FDQ chain B against the predicted model O15540: TM-score 0.99, RMSD 0.52 Å
- 1FDQ chain B against the predicted model O15540: TM-score 0.99, RMSD 0.52 Å
- 8IVL chain A against the predicted model O15540: TM-score 0.97, RMSD 0.53 Å
- 8IVF chain B against the predicted model O15540: TM-score 0.99, RMSD 0.53 Å
- 1FE3 chain A against the predicted model O15540: TM-score 0.98, RMSD 0.54 Å
Elsewhere
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