UniProt O15178
T-box transcription factor T (O15178)
T-box transcription factor T (UniProt O15178): 104 experimental structures on GenesisL1, 52 ligands bound, 16 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- O15178
- Protein
- T-box transcription factor T
- Experimental structures
- 104
- Predicted models
- 0
- Ligands
- 52
- Pockets
- 16 · 2 records with a druggable one
Structures
104 records of O15178 in the MolNFT archive: 104 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5QRF | PanDDA analysis group deposition -- Crystal Structure of human Brachyury in complex with Z373768900 | x-ray diffraction | A | CD, NUA | — |
| 5QRF | Pandda analysis group deposition -- crystal structure of human brachyury in complex with Z373768900 | x-ray diffraction | A | CD, NUA | — |
| 5QRG | PanDDA analysis group deposition -- Crystal Structure of human Brachyury in complex with Z275151340 | x-ray diffraction | A | CD, JHP | — |
| 5QRG | Pandda analysis group deposition -- crystal structure of human brachyury in complex with Z275151340 | x-ray diffraction | A | CD, JHP | — |
| 5QRH | PanDDA analysis group deposition -- Crystal Structure of human Brachyury in complex with Z32327641 | x-ray diffraction | A | CD, JMM | — |
| 5QRH | Pandda analysis group deposition -- crystal structure of human brachyury in complex with Z32327641 | x-ray diffraction | A | CD, JMM | — |
| 5QRI | PanDDA analysis group deposition -- Crystal Structure of human Brachyury in complex with Z2856434826 | x-ray diffraction | A | CD, NUY | — |
| 5QRI | Pandda analysis group deposition -- crystal structure of human brachyury in complex with Z2856434826 | x-ray diffraction | A | CD, NUY | — |
| 5QRJ | PanDDA analysis group deposition -- Crystal Structure of human Brachyury in complex with Z416341642 | x-ray diffraction | A | CD, NWP | — |
| 5QRJ | Pandda analysis group deposition -- crystal structure of human brachyury in complex with Z416341642 | x-ray diffraction | A | CD, NWP | — |
| 5QRK | PanDDA analysis group deposition -- Crystal Structure of human Brachyury in complex with Z275179758 | x-ray diffraction | A | CD, NWV | — |
| 5QRK | Pandda analysis group deposition -- crystal structure of human brachyury in complex with Z275179758 | x-ray diffraction | A | CD, NWV | — |
| 5QRL | PanDDA analysis group deposition -- Crystal Structure of human Brachyury in complex with Z437516460 | x-ray diffraction | A | CD, NWY | — |
| 5QRL | Pandda analysis group deposition -- crystal structure of human brachyury in complex with Z437516460 | x-ray diffraction | A | CD, NWY | — |
| 5QRM | PanDDA analysis group deposition -- Crystal Structure of human Brachyury in complex with Z1899842917 | x-ray diffraction | A | CD, K1A | — |
| 5QRM | Pandda analysis group deposition -- crystal structure of human brachyury in complex with Z1899842917 | x-ray diffraction | A | CD, K1A | — |
| 5QRN | PanDDA analysis group deposition -- Crystal Structure of human Brachyury in complex with Z54226006 | x-ray diffraction | A | CD, NX7 | — |
| 5QRN | Pandda analysis group deposition -- crystal structure of human brachyury in complex with Z54226006 | x-ray diffraction | A | CD, NX7 | — |
| 5QRO | PanDDA analysis group deposition -- Crystal Structure of human Brachyury in complex with Z1506050651 | x-ray diffraction | A | CD, NXJ | — |
| 5QRO | Pandda analysis group deposition -- crystal structure of human brachyury in complex with Z1506050651 | x-ray diffraction | A | CD, NXJ | — |
| 5QRP | PanDDA analysis group deposition -- Crystal Structure of human Brachyury in complex with Z2442270563 | x-ray diffraction | A | CD, NXM | — |
| 5QRP | Pandda analysis group deposition -- crystal structure of human brachyury in complex with Z2442270563 | x-ray diffraction | A | CD, NXM | — |
| 5QRQ | PanDDA analysis group deposition -- Crystal Structure of human Brachyury in complex with Z645232558 | x-ray diffraction | A | CD, NXS | — |
| 5QRQ | Pandda analysis group deposition -- crystal structure of human brachyury in complex with Z645232558 | x-ray diffraction | A | CD, NXS | — |
| 5QRR | PanDDA analysis group deposition -- Crystal Structure of human Brachyury in complex with Z31720228 | x-ray diffraction | A | CD, NY1 | — |
| 5QRR | Pandda analysis group deposition -- crystal structure of human brachyury in complex with Z31720228 | x-ray diffraction | A | CD, NY1 | — |
| 5QRS | PanDDA analysis group deposition -- Crystal Structure of human Brachyury in complex with Z1891773393 | x-ray diffraction | A | CD, NY4 | — |
| 5QRS | Pandda analysis group deposition -- crystal structure of human brachyury in complex with Z1891773393 | x-ray diffraction | A | CD, NY4 | — |
| 5QRT | PanDDA analysis group deposition -- Crystal Structure of human Brachyury in complex with Z31735562 | x-ray diffraction | A | CD, GWA | — |
| 5QRT | Pandda analysis group deposition -- crystal structure of human brachyury in complex with Z31735562 | x-ray diffraction | A | CD, GWA | — |
| 5QRU | PanDDA analysis group deposition -- Crystal Structure of human Brachyury in complex with Z235341991 | x-ray diffraction | A | CD, NY7 | — |
| 5QRU | Pandda analysis group deposition -- crystal structure of human brachyury in complex with Z235341991 | x-ray diffraction | A | CD, NY7 | — |
| 5QRV | PanDDA analysis group deposition -- Crystal Structure of human Brachyury in complex with Z198194396 | x-ray diffraction | A | CD, K2M | — |
| 5QRV | Pandda analysis group deposition -- crystal structure of human brachyury in complex with Z198194396 | x-ray diffraction | A | CD, K2M | — |
| 5QRW | PanDDA analysis group deposition -- Crystal Structure of human Brachyury in complex with Z1509882419 | x-ray diffraction | A | CD, NYV | — |
| 5QRW | Pandda analysis group deposition -- crystal structure of human brachyury in complex with Z1509882419 | x-ray diffraction | A | CD, NYV | — |
| 5QRX | PanDDA analysis group deposition -- Crystal Structure of human Brachyury in complex with Z364328788 | x-ray diffraction | A | CD, NZG | — |
| 5QRX | Pandda analysis group deposition -- crystal structure of human brachyury in complex with Z364328788 | x-ray diffraction | A | CD, NZG | — |
| 5QRY | PanDDA analysis group deposition -- Crystal Structure of human Brachyury in complex with Z2856434890 | x-ray diffraction | A | CD, NZD | — |
| 5QRY | Pandda analysis group deposition -- crystal structure of human brachyury in complex with Z2856434890 | x-ray diffraction | A | CD, NZD | — |
| 5QRZ | PanDDA analysis group deposition -- Crystal Structure of human Brachyury in complex with Z1998104358 | x-ray diffraction | A | CD, NZ7 | — |
| 5QRZ | Pandda analysis group deposition -- crystal structure of human brachyury in complex with Z1998104358 | x-ray diffraction | A | CD, NZ7 | — |
| 5QS0 | PanDDA analysis group deposition -- Crystal Structure of human Brachyury in complex with Z274555794 | x-ray diffraction | A | CD, NZ4 | — |
| 5QS0 | Pandda analysis group deposition -- crystal structure of human brachyury in complex with Z274555794 | x-ray diffraction | A | CD, NZ4 | — |
| 5QS1 | PanDDA analysis group deposition -- Crystal Structure of human Brachyury in complex with Z1954800564 | x-ray diffraction | A | CD, NZ1 | — |
| 5QS1 | Pandda analysis group deposition -- crystal structure of human brachyury in complex with Z1954800564 | x-ray diffraction | A | CD, NZ1 | — |
| 5QS2 | PanDDA analysis group deposition -- Crystal Structure of human Brachyury in complex with Z291279160 | x-ray diffraction | A | CD, LV4 | — |
| 5QS2 | Pandda analysis group deposition -- crystal structure of human brachyury in complex with Z291279160 | x-ray diffraction | A | CD, LV4 | — |
| 5QS3 | PanDDA analysis group deposition -- Crystal Structure of human Brachyury in complex with Z198195770 | x-ray diffraction | A | CD, LJA | — |
| 5QS3 | Pandda analysis group deposition -- crystal structure of human brachyury in complex with Z198195770 | x-ray diffraction | A | CD, LJA | — |
| 5QS4 | PanDDA analysis group deposition -- Crystal Structure of human Brachyury in complex with Z30820160 | x-ray diffraction | A | CD, JFP | — |
| 5QS4 | Pandda analysis group deposition -- crystal structure of human brachyury in complex with Z30820160 | x-ray diffraction | A | CD, JFP | — |
| 5QS5 | PanDDA analysis group deposition -- Crystal Structure of human Brachyury in complex with Z32400357 | x-ray diffraction | A | CD, NZJ | — |
| 5QS5 | Pandda analysis group deposition -- crystal structure of human brachyury in complex with Z32400357 | x-ray diffraction | A | CD, NZJ | — |
| 5QS6 | PanDDA analysis group deposition -- Crystal Structure of human Brachyury G177D variant in complex… | x-ray diffraction | A | K0G | — |
| 5QS6 | Pandda analysis group deposition -- crystal structure of human brachyury G177D variant in complex… | x-ray diffraction | A | K0G | — |
| 5QS7 | PanDDA analysis group deposition -- Crystal Structure of human Brachyury G177D variant in complex… | x-ray diffraction | A | JMM | 1 (best 0.41) |
| 5QS7 | Pandda analysis group deposition -- crystal structure of human brachyury G177D variant in complex… | x-ray diffraction | A | JMM | — |
| 5QS8 | PanDDA analysis group deposition -- Crystal Structure of human Brachyury G177D variant in complex… | x-ray diffraction | A | O0G | 1 (best 0.43) |
| 5QS8 | Pandda analysis group deposition -- crystal structure of human brachyury G177D variant in complex… | x-ray diffraction | A | O0G | — |
44 records more on the page itself.
Ligands
- CD · Cadmium ion · in 57 records
- UNL · Unknown ligand · in 5 records
- JMM · [4-(cyclopropanecarbonyl)piperazin-1-yl](furan-2-yl) methanone · in 4 records
- NA · Sodium ion · in 4 records
- PO4 · Phosphate ion · in 4 records
- 0WN · N-{4-[(3-chloro-4-fluorophenyl)amino]-7-[(3S)-tetrahydrofuran-3-yloxy]quinazolin-6-yl}-4-(dimethylamino)butanamide · in 2 records
- GWA · ~{N}-(3-acetamidophenyl)-2-methoxy-ethanamide · in 2 records
- IU4 · N-[4-(2-morpholin-4-yl-1,3-thiazol-4-yl) phenyl]ethanamide · in 2 records
- JFP · N-(4-methyl-1,3-thiazol-2-yl)propanamide · in 2 records
- JHJ · N-(4-methoxyphenyl)-N'-pyridin-4-ylurea · in 2 records
- JHP · 4-chloro-N-cyclopentyl-1-methyl-1H-pyrazole-3-carboxamide · in 2 records
- K0G · N-phenyl-N'-pyridin-3-ylurea · in 2 records
- K1A · 3-[(3,5-dimethyl-1,2-oxazol-4-yl)methyl]-5-methyl-1,3,4-thiadiazol-2(3H)-one · in 2 records
- K2M · 4-(furan-2-carbonyl)piperazine-1-carboxamide · in 2 records
- K2P · 2-(trifluoromethoxy)benzoic acid · in 2 records
- LJA · N-[3-(carbamoylamino)phenyl]acetamide · in 2 records
- LV4 · 1-[2-(trifluoromethyloxy)phenyl]thiourea · in 2 records
- NUA · N-(1-ethyl-1H-pyrazol-4-yl)cyclobutanecarboxamide · in 2 records
- NUY · [4-(propan-2-yl)piperazin-1-yl](thiophen-2-yl)methanone · in 2 records
- NVY · 1-ethyl-N-(2-fluorophenyl)piperidin-4-amine · in 2 records
- NWP · (2R)-N,2-dimethyl-N-(propan-2-yl)morpholine-4-sulfonamide · in 2 records
- NWV · N-[(1-methyl-1H-pyrazol-4-yl)methyl]furan-2-carboxamide · in 2 records
- NWY · N-[(6-methylpyridin-3-yl)methyl]cyclobutanecarboxamide · in 2 records
- NX7 · (2,6-difluorophenyl)(pyrrolidin-1-yl)methanone · in 2 records
- NXJ · (1S)-N,2,2-trimethyl-N-(pyridin-3-yl)cyclopropane-1-carboxamide · in 2 records
- NXM · 4-[(3-cyclopropyl-1,2,4-oxadiazol-5-yl) methyl]piperidine · in 2 records
- NXS · [1-(pyrimidin-2-yl)piperidin-4-yl]methanol · in 2 records
- NY1 · 2-(2-methyl-1,3-thiazol-4-yl)-1-(morpholin-4-yl)ethan-1-one · in 2 records
- NY4 · N-{4-[(1S)-1-aminoethyl]phenyl}cyclopropanecarboxamide · in 2 records
- NY7 · N-(2-methoxy-5-methylphenyl)glycinamide · in 2 records
Elsewhere
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