GL1X · GenesisL1 explorer

Ligand · 0WN

0WN · N-{4-[(3-chloro-4-fluorophenyl)amino]-7-[(3S)-tetrahydrofuran-3-yloxy]quinazolin-6-yl}-4-(dimethylamino)butanamide

0WN, N-{4-[(3-chloro-4-fluorophenyl)amino]-7-[(3S)-tetrahydrofuran-3-yloxy]quinazolin-6-yl}-4-(dimethylamino)butanamide (C24 H27 Cl F N5 O3, 488.0 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every…

Component
0WN
Formula
C24 H27 Cl F N5 O3
Class
ligand
Structures
2
PDB entries
1

Binding sites

0WN in 2 structures; the first of them:

  • 6ZU8 · Crystal structure of human Brachyury G177D variant in complex with Afatinib · 0WN A302 · binds ASP93, PRO120, SER121, CYS122, VAL123, HIS171, VAL173, ARG180 and 2 more
  • 6ZU8 · Crystal structure of human brachyury G177D variant in complex with afatinib · 0WN A302 · binds CYS122, VAL123, HIS171, VAL173, ARG180, ILE182

Residues it binds most

VAL 2, ARG 2, CYS 2, HIS 2, ILE 2, SER 1, ASP 1, PRO 1 (residue and the binding sites it lines).

Found with

  • ZN · Zinc ion

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.