UniProt O14764
Gamma-aminobutyric acid receptor subunit delta (O14764)
Gamma-aminobutyric acid receptor subunit delta (UniProt O14764): 14 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 57 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- O14764
- Protein
- Gamma-aminobutyric acid receptor subunit delta
- Experimental structures
- 14
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 57 · 7 records with a druggable one
Structures
15 records of O14764 in the MolNFT archive: 14 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7QN5 | Cryo-EM structure of human full-length extrasynaptic alpha4beta3delta GABA(A)R in complex with… | electron microscopy | E | CL, NAG, D10 | 8 (best 0.83) |
| 7QN5 | Cryo-EM structure of human full-length extrasynaptic ALPHA4BETA3DELTA GABA(A)R in complex with… | electron microscopy | E | CL, NAG, D10 | — |
| 7QN6 | Cryo-EM structure of human full-length beta3delta GABA(A)R in complex with nanobody Nb25 | electron microscopy | E | NAG | 7 (best 0.83) |
| 7QN6 | Cryo-EM structure of human full-length BETA3DELTA GABA(A)R in complex with nanobody NB25 | electron microscopy | E | NAG | — |
| 7QN7 | Cryo-EM structure of human full-length extrasynaptic alpha4beta3delta GABA(A)R in complex with… | electron microscopy | E | D10, NAG | 7 (best 0.81) |
| 7QN7 | Cryo-EM structure of human full-length extrasynaptic ALPHA4BETA3DELTA GABA(A)R in complex with… | electron microscopy | E | D10, NAG | — |
| 7QN8 | Cryo-EM structure of human full-length beta3delta GABA(A)R in complex with histamine and nanobody… | electron microscopy | E | NAG | 7 (best 0.83) |
| 7QN8 | Cryo-EM structure of human full-length BETA3DELTA GABA(A)R in complex with histamine and nanobody… | electron microscopy | E | NAG | — |
| 7QN9 | Cryo-EM structure of human full-length extrasynaptic alpha4beta3delta GABA(A)R in complex with… | electron microscopy | E | NAG | 10 (best 0.81) |
| 7QN9 | Cryo-EM structure of human full-length extrasynaptic ALPHA4BETA3DELTA GABA(A)R in complex with… | electron microscopy | E | NAG | — |
| 7QNC | Cryo-EM structure of human full-length extrasynaptic alpha4beta3delta GABA(A)R in complex with THIP… | electron microscopy | E | NAG, EI7 | 9 (best 0.82) |
| 7QNC | Cryo-EM structure of human full-length extrasynaptic ALPHA4BETA3DELTA GABA(A)R in complex with thip… | electron microscopy | E | NAG, EI7 | — |
| 7QND | Cryo-EM structure of human full-length extrasynaptic beta3delta GABA(A)R in complex with THIP… | electron microscopy | E | EI7, NAG | 9 (best 0.84) |
| 7QND | Cryo-EM structure of human full-length extrasynaptic BETA3DELTA GABA(A)R in complex with thip… | electron microscopy | E | EI7, NAG | — |
| O14764 | AlphaFold monomer V2.0 prediction for gamma-aminobutyric acid receptor subunit delta (O14764) | predicted | A | — | — |
Ligands
Experiment against prediction
- 7QN8 chain E against the predicted model O14764: TM-score 0.98, RMSD 1.08 Å
- 7QN8 chain E against the predicted model O14764: TM-score 0.98, RMSD 1.08 Å
- 7QND chain E against the predicted model O14764: TM-score 0.98, RMSD 1.10 Å
- 7QND chain E against the predicted model O14764: TM-score 0.98, RMSD 1.10 Å
- 7QN6 chain E against the predicted model O14764: TM-score 0.97, RMSD 1.15 Å
- 7QN6 chain E against the predicted model O14764: TM-score 0.97, RMSD 1.15 Å
- 7QN7 chain E against the predicted model O14764: TM-score 0.97, RMSD 1.18 Å
- 7QN7 chain E against the predicted model O14764: TM-score 0.97, RMSD 1.18 Å
- 7QNC chain E against the predicted model O14764: TM-score 0.97, RMSD 1.17 Å
- 7QNC chain E against the predicted model O14764: TM-score 0.97, RMSD 1.17 Å
Elsewhere
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