UniProt O14607
Histone demethylase uty (O14607)
Histone demethylase uty (UniProt O14607): 22 experimental structures and 1 predicted model on GenesisL1, 6 ligands bound, 44 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O14607
- Protein
- Histone demethylase uty
- Experimental structures
- 22
- Predicted models
- 1
- Ligands
- 6
- Pockets
- 44 · 4 records with a druggable one
Structures
23 records of O14607 in the MolNFT archive: 22 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3ZLI | Crystal structure of JmjC domain of human histone demethylase UTY | x-ray diffraction | A, B | — | — |
| 3ZLI | Crystal structure of jmjc domain of human histone demethylase uty | x-ray diffraction | A, B | — | — |
| 3ZPO | Crystal structure of JmjC domain of human histone demethylase UTY with bound GSK J1 | x-ray diffraction | A, B | — | — |
| 3ZPO | Crystal structure of jmjc domain of human histone demethylase uty with bound gsk J1 | x-ray diffraction | A, B | — | — |
| 4UF0 | Crystal structure of JmjC domain of human histone demethylase UTY in complex with epitherapuetic… | x-ray diffraction | A, B | — | — |
| 4UF0 | Crystal structure of jmjc domain of human histone demethylase uty in complex with epitherapuetic… | x-ray diffraction | A, B | — | — |
| 5FXV | Crystal structure of JmjC domain of human histone demethylase UTY in complex with N05859b | x-ray diffraction | A, B | ZN, MN, MN1 | 9 (best 0.79) |
| 5FXV | Crystal structure of jmjc domain of human histone demethylase uty in complex with N05859B | x-ray diffraction | A, B | — | — |
| 5FXW | Crystal structure of JmjC domain of human histone demethylase UTY in complex with fumarate | x-ray diffraction | A, B | ZN, MN, FUM | 9 (best 0.80) |
| 5FXW | Crystal structure of jmjc domain of human histone demethylase uty in complex with fumarate | x-ray diffraction | A, B | — | — |
| 5FXX | Crystal structure of JmjC domain of human histone demethylase UTY in complex with oxaloacetate | x-ray diffraction | A, B | — | — |
| 5FXX | Crystal structure of jmjc domain of human histone demethylase uty in complex with oxaloacetate | x-ray diffraction | A, B | — | — |
| 5FXZ | Crystal structure of JmjC domain of human histone demethylase UTY in complex with citrate | x-ray diffraction | A, B | MN, ZN | — |
| 5FXZ | Crystal structure of jmjc domain of human histone demethylase uty in complex with citrate | x-ray diffraction | A, B | — | — |
| 5FY0 | Crystal structure of JmjC domain of human histone demethylase UTY in complex with L-malate | x-ray diffraction | A, B | — | — |
| 5FY0 | Crystal structure of jmjc domain of human histone demethylase uty in complex with L-malate | x-ray diffraction | A, B | — | — |
| 5FY1 | Crystal structure of JmjC domain of human histone demethylase UTY in complex with N08619b | x-ray diffraction | A, B | ZN, MN, 0R0 | 11 (best 0.77) |
| 5FY1 | Crystal structure of jmjc domain of human histone demethylase uty in complex with N08619B | x-ray diffraction | A, B | — | — |
| 5FY7 | Crystal structure of JmjC domain of human histone demethylase UTY in complex with succinate | x-ray diffraction | A, B | MN, ZN | — |
| 5FY7 | Crystal structure of jmjc domain of human histone demethylase uty in complex with succinate | x-ray diffraction | A, B | — | — |
| 5FYM | Crystal structure of JmjC domain of human histone demethylase UTY in complex with… | x-ray diffraction | A, B | MN, 2HG, ZN | — |
| 5FYM | Crystal structure of jmjc domain of human histone demethylase uty in complex with… | x-ray diffraction | A, B | — | — |
| O14607 | AlphaFold monomer V2.0 prediction for histone demethylase uty (O14607) | predicted | A | — | 15 (best 0.81) |
Ligands
Experiment against prediction
- 5FXW chain B against the predicted model O14607: TM-score 0.99, RMSD 0.77 Å
- 5FXW chain B against the predicted model O14607: TM-score 0.99, RMSD 0.77 Å
- 3ZLI chain B against the predicted model O14607: TM-score 0.99, RMSD 0.78 Å
- 3ZLI chain B against the predicted model O14607: TM-score 0.99, RMSD 0.78 Å
- 5FXV chain B against the predicted model O14607: TM-score 0.99, RMSD 0.90 Å
- 5FXV chain B against the predicted model O14607: TM-score 0.99, RMSD 0.90 Å
- 3ZPO chain B against the predicted model O14607: TM-score 0.99, RMSD 0.86 Å
- 3ZPO chain B against the predicted model O14607: TM-score 0.99, RMSD 0.86 Å
- 5FXZ chain B against the predicted model O14607: TM-score 0.99, RMSD 0.86 Å
- 5FXZ chain B against the predicted model O14607: TM-score 0.99, RMSD 0.86 Å
Elsewhere
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