UniProt O14079
DNA damage response protein Mdb1 (O14079)
DNA damage response protein Mdb1 (UniProt O14079): 6 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O14079
- Protein
- DNA damage response protein Mdb1
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 1 · 0 records with a druggable one
Structures
7 records of O14079 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4S3H | Crystal structure of S. pombe Mdb1 FHA domain | x-ray diffraction | A, B, C, D | — | — |
| 4S3H | Crystal structure of S. pombe MDB1 fha domain | x-ray diffraction | A, B, C, D | — | — |
| 6HM4 | Crystal structure of RAD4 BRCT1,2 in complex with a MDB1 phosphopeptide | x-ray diffraction | B | — | — |
| 7P0J | Crystal structure of S.pombe Mdb1 BRCT domains | x-ray diffraction | A | NA, MG | 1 (best 0.39) |
| 7P0J | Crystal structure of S.POMBE MDB1 brct domains | x-ray diffraction | A | NA | — |
| 7P0L | Crystal structure of S.POMBE MDB1 brct domains in complex with a H2A phosphopeptide | x-ray diffraction | A, B | — | — |
| O14079 | AlphaFold monomer V2.0 prediction for DNA damage response protein MDB1 (O14079) | predicted | A | — | — |
Ligands
Experiment against prediction
- 7P0L chain A against the predicted model O14079: TM-score 0.95, RMSD 1.20 Å
- 7P0J chain A against the predicted model O14079: TM-score 0.95, RMSD 1.23 Å
- 7P0J chain A against the predicted model O14079: TM-score 0.95, RMSD 1.23 Å
- 4S3H chain A against the predicted model O14079: TM-score 0.70, RMSD 2.19 Å
- 4S3H chain A against the predicted model O14079: TM-score 0.70, RMSD 2.19 Å
- 4S3H chain B against the predicted model O14079: TM-score 0.68, RMSD 2.38 Å
- 4S3H chain B against the predicted model O14079: TM-score 0.68, RMSD 2.38 Å
- 4S3H chain C against the predicted model O14079: TM-score 0.67, RMSD 2.46 Å
- 4S3H chain C against the predicted model O14079: TM-score 0.67, RMSD 2.46 Å
- 6HM4 chain B against the predicted model O14079: TM-score 0.44, RMSD 1.05 Å
Elsewhere
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