UniProt O08967
Cytohesin-3,ADP-ribosylation factor 6 (O08967)
Cytohesin-3,ADP-ribosylation factor 6 (UniProt O08967): 16 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 7 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O08967
- Protein
- Cytohesin-3,ADP-ribosylation factor 6
- Experimental structures
- 16
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 7 · 1 record with a druggable one
Structures
17 records of O08967 in the MolNFT archive: 16 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1FGY | GRP1 pH domain with INS(1,3,4,5)P4 | x-ray diffraction | A | — | — |
| 1FGY | GRP1 pH domain with INS(1,3,4,5)P4 | x-ray diffraction | A | — | — |
| 1FGZ | GRP1 pH domain (unliganded) | x-ray diffraction | A | — | — |
| 1FGZ | GRP1 pH domain (unliganded) | x-ray diffraction | A | — | — |
| 1FHX | Structure of the pleckstrin homology domain from GRP1 in complex with inositol… | x-ray diffraction | A, B | — | — |
| 1FHX | Structure of the pleckstrin homology domain from GRP1 in complex with inositol… | x-ray diffraction | A, B | — | — |
| 1U2B | Triglycine variant of the Grp1 Pleckstrin Homology Domain unliganded | x-ray diffraction | A | — | — |
| 1U2B | Triglycine variant of the GRP1 pleckstrin homology domain unliganded | x-ray diffraction | A | — | — |
| 2R09 | Crystal Structure of Autoinhibited Form of Grp1 Arf GTPase Exchange Factor | x-ray diffraction | A, B | — | — |
| 2R09 | Crystal structure of autoinhibited form of GRP1 arf GTPase exchange factor | x-ray diffraction | A, B | — | — |
| 2R0D | Crystal Structure of Autoinhibited Form of Grp1 Arf GTPase Exchange Factor | x-ray diffraction | A, B | — | — |
| 2R0D | Crystal structure of autoinhibited form of GRP1 arf GTPase exchange factor | x-ray diffraction | A, B | — | — |
| 6BBP | Model for compact volume of truncated monomeric Cytohesin-3 (Grp1; amino acids 63-399) E161A 6GS… | electron microscopy | A | GTP, MG, 4IP | 7 (best 0.70) |
| 6BBP | Model for compact volume of truncated monomeric cytohesin-3 (GRP1; amino acids 63-399) E161A 6GS… | electron microscopy | A | GTP, MG, 4IP | — |
| 6BBQ | Model for extended volume of truncated monomeric Cytohesin-3 (Grp1; amino acids 63-399) E161A Arf6… | electron microscopy | A | GTP, MG, 4IP | — |
| 6BBQ | Model for extended volume of truncated monomeric cytohesin-3 (GRP1; amino acids 63-399) E161A ARF6… | electron microscopy | A | GTP, MG, 4IP | — |
| O08967 | AlphaFold monomer V2.0 prediction for cytohesin-3 (O08967) | predicted | A | — | — |
Ligands
Experiment against prediction
- 1FHX chain A against the predicted model O08967: TM-score 0.95, RMSD 1.37 Å
- 1FHX chain A against the predicted model O08967: TM-score 0.95, RMSD 1.37 Å
- 6BBQ chain A against the predicted model P62330: TM-score 0.32, RMSD 1.30 Å
- 6BBQ chain A against the predicted model P62330: TM-score 0.32, RMSD 1.30 Å
- 6BBP chain A against the predicted model P62330: TM-score 0.32, RMSD 1.30 Å
- 6BBP chain A against the predicted model P62330: TM-score 0.32, RMSD 1.30 Å
- 1FHX chain B against the predicted model O08967: TM-score 0.94, RMSD 1.46 Å
- 1FHX chain B against the predicted model O08967: TM-score 0.94, RMSD 1.46 Å
- 1FGY chain A against the predicted model O08967: TM-score 0.92, RMSD 1.41 Å
- 1FGY chain A against the predicted model O08967: TM-score 0.92, RMSD 1.41 Å
Elsewhere
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