UniProt M1JS91
Isoprenyl diphosphate synthase (M1JS91)
Isoprenyl diphosphate synthase (UniProt M1JS91), EC 2.5.1.1: 11 experimental structures on GenesisL1, 8 ligands bound, 92 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- M1JS91
- Protein
- Isoprenyl diphosphate synthase
- EC
- 2.5.1.1
- Experimental structures
- 11
- Predicted models
- 0
- Ligands
- 8
- Pockets
- 92 · 11 records with a druggable one
Structures
11 records of M1JS91 in the MolNFT archive: 11 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8A6U | PcIDS1 in complex with Mg2+ | x-ray diffraction | A, B | MG | 7 (best 0.81) |
| 8A6V | PcIDS1 in complex with Mg2+ and IPP | x-ray diffraction | A, B | MG, IPE | 9 (best 0.81) |
| 8A6Z | PcIDS1 in complex with Mn2+ and IPP | x-ray diffraction | A, B, C, D, E, F | MN, IPE | 20 (best 0.82) |
| 8A73 | PcIDS1 in complex with Mn2+ and GPP | x-ray diffraction | A, B | MG, MN, GPP | 7 (best 0.81) |
| 8A78 | PcIDS1_F315A in complex with Mg2+/Mn2+ and GPP | x-ray diffraction | A, B | MN, MG, POP, GPP | 7 (best 0.77) |
| 8A7A | PcIDS1 in complex with Mg2+ and 3-Br-GPP | x-ray diffraction | A, B | MG, L7X | 7 (best 0.79) |
| 8A7B | PcIDS1_D319N in complex with Mg2+ and 3-Br-GPP | x-ray diffraction | A, B | MG, CO3, L7X | 7 (best 0.77) |
| 8A7J | PcIDS1 in complex with Mn2+, IPP, and ZOL | x-ray diffraction | A, B | MN, IPE, ZOL | 10 (best 0.81) |
| 8A7K | PcIDS1 in complex with Mg2+/Mn2+, IPP, and ZOL | x-ray diffraction | A, B | MN, MG, IPE, ZOL | 10 (best 0.81) |
| 8A7L | PcIDS1 in complex with Mg2+, GPP, and ZOL | x-ray diffraction | A | MG, ZOL, GPP | 3 (best 0.80) |
| 8A7U | PcIDS1_F315D in complex with Mg2+ and GPP | x-ray diffraction | A, B | MG, GPP | 5 (best 0.78) |
Ligands
- MG · Magnesium ion · in 9 records
- MN · Manganese (II) ion · in 5 records
- GPP · Geranyl diphosphate · in 4 records
- IPE · 3-methylbut-3-enyl trihydrogen diphosphate · in 4 records
- ZOL · Zoledronic acid · in 3 records
- L7X · [(2Z)-3-bromanyl-7-methyl-octa-2,6-dienyl] phosphono hydrogen phosphate · in 2 records
- CO3 · Carbonate ion · in 1 record
- POP · Pyrophosphate 2- · in 1 record
Elsewhere
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