UniProt L0T911
Penicillin-binding protein pbpb (L0T911)
Penicillin-binding protein pbpb (UniProt L0T911): 10 experimental structures and 1 predicted model on GenesisL1, 7 ligands bound, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- L0T911
- Protein
- Penicillin-binding protein pbpb
- Experimental structures
- 10
- Predicted models
- 1
- Ligands
- 7
- Pockets
- 3 · 1 record with a druggable one
Structures
11 records of L0T911 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6KGH | Crystal structure of Penicillin binding protein 3 (PBP3) from Mycobacterium tuerculosis (apo-form) | x-ray diffraction | A | CO, NA | — |
| 6KGH | Crystal structure of penicillin binding protein 3 (PBP3) from mycobacterium tuerculosis (apo-form) | x-ray diffraction | A | CO, NA | — |
| 6KGS | Crystal structure of Penicillin binding protein 3 (PBP3) from Mycobacterium tuerculosis, complexed… | x-ray diffraction | A | MER, CO | — |
| 6KGS | Crystal structure of penicillin binding protein 3 (PBP3) from mycobacterium tuerculosis, complexed… | x-ray diffraction | A | MER, CO | — |
| 6KGT | Crystal structure of Penicillin binding protein 3 (PBP3) from Mycobacterium tuerculosis, complexed… | x-ray diffraction | A | SFR, CO | — |
| 6KGT | Crystal structure of penicillin binding protein 3 (PBP3) from mycobacterium tuerculosis, complexed… | x-ray diffraction | A | SFR, CO | — |
| 6KGU | Crystal structure of Penicillin binding protein 3 (PBP3) from Mycobacterium tuerculosis, complexed… | x-ray diffraction | A | AZR, CO | — |
| 6KGU | Crystal structure of penicillin binding protein 3 (PBP3) from mycobacterium tuerculosis, complexed… | x-ray diffraction | A | AZR, CO | — |
| 6KGV | Crystal structure of penicillin binding protein 3 (PBP3) from mycobacterium tuerculosis, complexed… | x-ray diffraction | A | CO, AXL | — |
| 6KGW | Crystal structure of penicillin binding protein 3 (PBP3) from mycobacterium tuerculosis, complexed… | x-ray diffraction | A | CO, AIX | — |
| L0T911 | AlphaFold monomer V2.0 prediction for penicillin-binding protein pbpb (L0T911) | predicted | A | — | 3 (best 0.56) |
Ligands
- CO · Cobalt (II) ion · in 10 records
- AZR · 2-({[(1Z)-1-(2-amino-1,3-thiazol-4-yl)-2-oxo-2-{[(2S, 3S)-1-oxo-3-(sulfoamino)butan-2-yl]amino}ethylidene]amino}oxy)-2-methylpropanoic acid · in 2 records
- MER · (4R,5S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-5-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-4-methyl-4,5-dihydro-1H-pyrrole-2-carboxylic acid · in 2 records
- NA · Sodium ion · in 2 records
- SFR · (2R)-2-[(1S,2R)-1-carboxy-2-hydroxypropyl]-5-[(2R)-oxolan-2-yl]-2,3-dihydro-1,3-thiazole-4-carboxylic acid · in 2 records
- AIX · (2R,4S)-2-[(1R)-1-{[(2R)-2-amino-2-phenylacetyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid · in 1 record
- AXL · 2-{1-[2-amino-2-(4-hydroxy-phenyl)-acetylamino]-2-oxo-ethyl}-5,5-dimethyl-thiazolidine-4-carboxylic acid · in 1 record
Experiment against prediction
- 6KGH chain A against the predicted model L0T911: TM-score 0.99, RMSD 0.70 Å
- 6KGH chain A against the predicted model L0T911: TM-score 0.99, RMSD 0.70 Å
- 6KGV chain A against the predicted model L0T911: TM-score 0.99, RMSD 0.78 Å
- 6KGU chain A against the predicted model L0T911: TM-score 0.99, RMSD 0.79 Å
- 6KGU chain A against the predicted model L0T911: TM-score 0.99, RMSD 0.79 Å
- 6KGT chain A against the predicted model L0T911: TM-score 0.99, RMSD 0.81 Å
- 6KGT chain A against the predicted model L0T911: TM-score 0.99, RMSD 0.81 Å
- 6KGS chain A against the predicted model L0T911: TM-score 0.99, RMSD 0.81 Å
- 6KGS chain A against the predicted model L0T911: TM-score 0.99, RMSD 0.81 Å
- 6KGW chain A against the predicted model L0T911: TM-score 0.99, RMSD 0.84 Å
Elsewhere
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