UniProt L0E4H0
FAD monooxygenase (L0E4H0)
FAD monooxygenase (UniProt L0E4H0): 10 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 27 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- L0E4H0
- Protein
- FAD monooxygenase
- Experimental structures
- 10
- Predicted models
- 1
- Ligands
- 5
- Pockets
- 27 · 6 records with a druggable one
Structures
11 records of L0E4H0 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6PVF | Crystal structure of PhqK in complex with malbrancheamide B | x-ray diffraction | A | FAD, MB5 | 4 (best 0.85) |
| 6PVF | Crystal structure of phqk in complex with malbrancheamide B | x-ray diffraction | A | FAD, MB5 | — |
| 6PVG | Crystal structure of ligand free PhqK | x-ray diffraction | A | FAD | 4 (best 0.83) |
| 6PVG | Crystal structure of ligand free phqk | x-ray diffraction | A | FAD | — |
| 6PVH | Crystal structure of PhqK in complex with paraherquamide K | x-ray diffraction | A | OZ4, FAD | 5 (best 0.86) |
| 6PVH | Crystal structure of phqk in complex with paraherquamide K | x-ray diffraction | A | OZ4, FAD | — |
| 6PVI | Crystal structure of PhqK in complex with paraherquamide L | x-ray diffraction | A | OZ7, FAD | 6 (best 0.86) |
| 6PVI | Crystal structure of phqk in complex with paraherquamide L | x-ray diffraction | A | OZ7, FAD | — |
| 6PVJ | Crystal structure of PhqK in complex with malbrancheamide C | x-ray diffraction | A | FAD, OZA | 4 (best 0.86) |
| 6PVJ | Crystal structure of phqk in complex with malbrancheamide C | x-ray diffraction | A | FAD, OZA | — |
| L0E4H0 | AlphaFold monomer V2.0 prediction for FAD-dependent monooxygenase phqk (L0E4H0) | predicted | A | — | 4 (best 0.85) |
Ligands
- FAD · Flavin-adenine dinucleotide · in 10 records
- MB5 · (5as,12as,13as)-9-chloro-12,12-dimethyl-2,3,11,12,12A, 13-hexahydro-1H,5H,6H-5A,13A-(epiminomethano) indolizino[7,6-b]carbazol-14-one · in 2 records
- OZ4 · (7as,12s,12ar,13as)-3,3,12,14,14-pentamethyl-3,7,11,12, 13,13A,14,15-octahydro-8H,10H-7A,12A-(epiminomethano) indolizino[6,7-h]pyrano[3,2-a]carbazol-16-one · in 2 records
- OZ7 · (8as,13s,13ar,14as)-4,4,13,15,15-pentamethyl-12,13,14, 14A,15,16-hexahydro-4H,8H,9H,11H-8A,13A-(epiminomethano)[1,4]dioxepino[2,3-a]indolizino[6,7-h]carbazol-17-one · in 2 records
- OZA · (5as,12as,13as)-9-bromo-12,12-dimethyl-2,3,11,12,12A, 13-hexahydro-1H,5H,6H-5A,13A-(epiminomethano) indolizino[7,6-b]carbazol-14-one · in 2 records
Experiment against prediction
- 6PVI chain A against the predicted model L0E4H0: TM-score 0.94, RMSD 1.97 Å
- 6PVI chain A against the predicted model L0E4H0: TM-score 0.94, RMSD 1.97 Å
- 6PVF chain A against the predicted model L0E4H0: TM-score 0.94, RMSD 2.10 Å
- 6PVF chain A against the predicted model L0E4H0: TM-score 0.94, RMSD 2.10 Å
- 6PVH chain A against the predicted model L0E4H0: TM-score 0.94, RMSD 2.10 Å
- 6PVH chain A against the predicted model L0E4H0: TM-score 0.94, RMSD 2.10 Å
- 6PVJ chain A against the predicted model L0E4H0: TM-score 0.94, RMSD 2.12 Å
- 6PVJ chain A against the predicted model L0E4H0: TM-score 0.94, RMSD 2.12 Å
- 6PVG chain A against the predicted model L0E4H0: TM-score 0.94, RMSD 2.19 Å
- 6PVG chain A against the predicted model L0E4H0: TM-score 0.94, RMSD 2.19 Å
Elsewhere
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