UniProt K0BRG7
Spike glycoprotein (K0BRG7)
Spike glycoprotein (UniProt K0BRG7): 22 experimental structures on GenesisL1, 7 ligands bound, 179 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- K0BRG7
- Protein
- Spike glycoprotein
- Experimental structures
- 22
- Predicted models
- 0
- Ligands
- 7
- Pockets
- 179 · 9 records with a druggable one
Structures
22 records of K0BRG7 in the MolNFT archive: 22 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4KQZ | structure of the receptor binding domain (RBD) of MERS-CoV spike | x-ray diffraction | A, B | — | — |
| 4KQZ | Structure of the receptor binding domain (rbd) of MERS-cov spike | x-ray diffraction | A, B | — | — |
| 4KR0 | Complex structure of MERS-CoV spike RBD bound to CD26 | x-ray diffraction | B | — | — |
| 4KR0 | Complex structure of MERS-cov spike rbd bound to CD26 | x-ray diffraction | B | — | — |
| 4MOD | Structure of the MERS-CoV fusion core | x-ray diffraction | A, B | — | — |
| 4MOD | Structure of the MERS-cov fusion core | x-ray diffraction | A, B | — | — |
| 6Q04 | MERS-cov S structure in complex with 5-N-acetyl neuraminic acid | electron microscopy | A, B, C | NAG, BMA, MAN, SIA | — |
| 6Q05 | MERS-cov S structure in complex with sialyl-lewisx | electron microscopy | A, B, C | NAG, BMA, MAN, SIA | — |
| 6Q06 | MERS-cov S structure in complex with 2,3-sialyl-N-acetyl-lactosamine | electron microscopy | A, B, C | NAG, BMA, MAN, SIA | — |
| 6Q07 | MERS-CoV S structure in complex with 2,6-sialyl-N-acetyl-lactosamine | electron microscopy | A, B, C | NAG, BMA, MAN, GAL, SIA, FOL | 20 (best 0.84) |
| 6Q07 | MERS-cov S structure in complex with 2,6-sialyl-N-acetyl-lactosamine | electron microscopy | A, B, C | NAG, BMA, MAN, GAL, SIA | — |
| 7V3L | MERS S ectodomain trimer in complex with neutralizing antibody 6516 | electron microscopy | A, B, C | — | 20 (best 0.82) |
| 7V3L | MERS S ectodomain trimer in complex with neutralizing antibody 6516 | electron microscopy | A, B, C | — | — |
| 7V5K | MERS S ectodomain trimer in complex with neutralizing antibody 0722 (state 1) | electron microscopy | A, B, C | — | — |
| 7V5K | MERS S ectodomain trimer in complex with neutralizing antibody 0722 (state 1) | electron microscopy | A, B, C | — | — |
| 7V6O | MERS S ectodomain trimer in complex with neutralizing antibody 111 (state 2) | electron microscopy | A, B, C | — | 19 (best 0.88) |
| 7X2A | MERS-CoV spike complex with S41 neutralizing antibody Fab Class1 (1u2d RBD with 1Fab) | electron microscopy | A, B, C | — | 20 (best 0.83) |
| 7YMT | Cryo-EM structure of MERS-CoV spike protein, Two RBD-up conformation 2 | electron microscopy | A, B, C | NAG, BMA, MAN, FUC | 20 (best 0.88) |
| 7YMW | Cryo-EM structure of MERS-CoV spike protein, One RBD-up conformation 4 | electron microscopy | A, B, C | NAG, MAN | 20 (best 0.90) |
| 7YMY | Cryo-EM structure of MERS-CoV spike protein, One RBD-up conformation 1 | electron microscopy | A, B, C | NAG, BMA, MAN | 20 (best 0.88) |
| 7YMZ | Cryo-EM structure of MERS-CoV spike protein, intermediate conformation | electron microscopy | A, B, C | NAG, BMA, MAN, FUC | 20 (best 0.87) |
| 7YN0 | Cryo-EM structure of MERS-CoV spike protein, all RBD-down conformation | electron microscopy | A, B, C | NAG, BMA, MAN, FUC | 20 (best 0.85) |
Ligands
- MAN · alpha-D-mannopyranose · in 10 records
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 10 records
- BMA · beta-D-mannopyranose · in 9 records
- SIA · N-acetyl-alpha-neuraminic acid · in 5 records
- FUC · alpha-L-fucopyranose · in 3 records
- GAL · beta-D-galactopyranose · in 2 records
- FOL · Folic acid · in 1 record
Elsewhere
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