UniProt I3LGM4
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (I3LGM4)
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (UniProt I3LGM4): 90 experimental structures on GenesisL1, 7 ligands bound, 31 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- I3LGM4
- Protein
- NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11
- Experimental structures
- 90
- Predicted models
- 0
- Ligands
- 7
- Pockets
- 31 · 25 records with a druggable one
Structures
90 records of I3LGM4 in the MolNFT archive: 90 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5GPN | Architecture of mammalian respirasome | electron microscopy | Ag | — | — |
| 5GUP | Cryo-EM structure of mammalian respiratory supercomplex I1III2IV1 | electron microscopy | V | CDL, PLX, PEE | — |
| 7V2C | Active state complex I from Q10 dataset | electron microscopy | V | CDL, PEE, PLX | 1 (best 0.82) |
| 7V2C | Active state complex I from Q10 dataset | electron microscopy | V | CDL, PEE, PLX | — |
| 7V2D | Deactive state complex I from Q10 dataset | electron microscopy | V | CDL, PEE, PLX | — |
| 7V2D | Deactive state complex I from Q10 dataset | electron microscopy | V | CDL, PEE, PLX | — |
| 7V2E | Active state complex I from Q10-NADH dataset | electron microscopy | V | CDL, PEE, PLX | 2 (best 0.82) |
| 7V2E | Active state complex I from Q10-NADH dataset | electron microscopy | V | CDL, PEE, PLX | — |
| 7V2F | Deactive state complex I from Q10-NADH dataset | electron microscopy | V | CDL, PEE, PLX | — |
| 7V2F | Deactive state complex I from Q10-NADH dataset | electron microscopy | V | CDL, PEE, PLX | — |
| 7V2H | Active state complex I from DQ-NADH dataset | electron microscopy | V | CDL, PEE, PLX | — |
| 7V2H | Active state complex I from dq-NADH dataset | electron microscopy | V | CDL, PEE, PLX | — |
| 7V2K | Deactive state complex I from DQ-NADH dataset | electron microscopy | V | PEE, PLX | — |
| 7V2K | Deactive state complex I from dq-NADH dataset | electron microscopy | V | PEE, PLX | — |
| 7V2R | Active state complex I from Q1-NADH dataset | electron microscopy | V | CDL, PEE, PLX | 1 (best 0.83) |
| 7V2R | Active state complex I from Q1-NADH dataset | electron microscopy | V | CDL, PEE, PLX | — |
| 7V30 | Deactive state complex I from Q1-NADH dataset | electron microscopy | V | PEE, CDL, PLX | — |
| 7V30 | Deactive state complex I from Q1-NADH dataset | electron microscopy | V | PEE, CDL, PLX | — |
| 7V31 | Active state complex I from rote dataset | electron microscopy | V | CDL, PEE, PLX | — |
| 7V31 | Active state complex I from rotenone dataset | electron microscopy | V | CDL, PEE, PLX | — |
| 7V32 | Deactive state complex I from rote dataset | electron microscopy | V | PEE, PLX | — |
| 7V32 | Deactive state complex I from rotenone dataset | electron microscopy | V | PEE, PLX | — |
| 7V33 | Active state complex I from rote -NADH dataset | electron microscopy | V | CDL, PEE, PLX | 1 (best 0.83) |
| 7V33 | Active state complex I from rotenone-NADH dataset | electron microscopy | V | CDL, PEE, PLX | — |
| 7V3M | Deactive state complex I from rote -NADH dataset | electron microscopy | V | PEE | — |
| 7V3M | Deactive state complex I from rotenone-NADH dataset | electron microscopy | V | PEE | — |
| 7VBL | Membrane arm of active state CI from DQ-NADH dataset | electron microscopy | V | CDL, PEE, PLX | 1 (best 0.82) |
| 7VBL | Membrane arm of active state ci from dq-NADH dataset | electron microscopy | V | CDL, PEE, PLX | — |
| 7VBP | Membrane arm of deactive state CI from DQ-NADH dataset | electron microscopy | V | CDL, PEE, PLX | — |
| 7VBP | Membrane arm of deactive state ci from dq-NADH dataset | electron microscopy | V | CDL, PEE, PLX | — |
| 7VC0 | Membrane arm of active state CI from Rote -NADH dataset | electron microscopy | V | CDL, PEE, PLX | — |
| 7VC0 | Membrane arm of active state ci from rotenone-NADH dataset | electron microscopy | V | CDL, PEE, PLX | — |
| 7VWL | Membrane arm of deactive state CI from rote -NADH dataset | electron microscopy | V | CDL, PEE, PLX | 1 (best 0.77) |
| 7VWL | Membrane arm of deactive state ci from rotenone-NADH dataset | electron microscopy | V | CDL, PEE, PLX | — |
| 7VXS | Membrane arm of active state CI from Q10 dataset | electron microscopy | V | CDL, PEE | 1 (best 0.81) |
| 7VY1 | Membrane arm of deactive state CI from Q10 dataset | electron microscopy | V | CDL, PEE, PLX | 1 (best 0.78) |
| 7VY9 | Membrane arm of active state CI from Q10-NADH dataset | electron microscopy | V | CDL, PEE, PLX | 3 (best 0.82) |
| 7VYE | Membrane arm of deactive state CI from Q10-NADH dataset | electron microscopy | V | PEE, CDL | 1 (best 0.76) |
| 7VYG | Membrane arm of active state CI from rote dataset | electron microscopy | V | CDL, PEE, PLX | — |
| 7VYI | Membrane arm of deactive state CI from Rote dataset | electron microscopy | V | PEE, PLX | 1 (best 0.78) |
| 7VYS | Membrane arm of active state CI from Q1-NADH dataset | electron microscopy | V | CDL, PEE, PLX | 2 (best 0.81) |
| 7VZ8 | Membrane arm of deactive state CI from Q1-NADH dataset | electron microscopy | V | CDL, PEE, PLX | 1 (best 0.85) |
| 7VZV | Active state CI from Q10 dataset, Subclass 1 | electron microscopy | V | CDL, PEE | — |
| 7VZW | Active state CI from Q10 dataset, Subclass 2 | electron microscopy | V | CDL, PEE | 1 (best 0.81) |
| 7W00 | Deactive state CI from Q10 dataset, Subclass 1 | electron microscopy | V | CDL, PEE, PLX | — |
| 7W0H | Deactive state CI from Q10 dataset, Subclass 2 | electron microscopy | V | CDL, PEE, PLX | — |
| 7W0R | Active state CI from Q10-NADH dataset, Subclass 1 | electron microscopy | V | CDL, PEE, PLX | 2 (best 0.82) |
| 7W0Y | Active state CI from Q10-NADH dataset, Subclass 2 | electron microscopy | V | CDL, PEE, PLX | — |
| 7W1O | Deactive state CI from Q10-NADH dataset, Subclass 1 | electron microscopy | V | CDL, PEE | — |
| 7W1P | Deactive state CI from Q10-NADH dataset, Subclass 2 | electron microscopy | V | CDL, PEE | — |
| 7W1T | Active state CI from Rote dataset, Subclass 1 | electron microscopy | V | CDL, PEE, PLX | — |
| 7W1U | Active state CI from Rote dataset, Subclass 2 | electron microscopy | V | CDL, PEE, PLX | — |
| 7W1V | Active state CI from Rote -NADH dataset, Subclass 1 | electron microscopy | V | CDL, PEE, PLX | 1 (best 0.82) |
| 7W1Z | Active state CI from Rote -NADH dataset, Subclass 2 | electron microscopy | V | CDL, PEE, PLX | — |
| 7W20 | Active state CI from Rote -NADH dataset, Subclass 3 | electron microscopy | V | CDL, PEE, PLX | — |
| 7W2K | Deactive state CI from Rote -NADH dataset, Subclass 1 | electron microscopy | V | PEE, PLX | — |
| 7W2L | Deactive state CI from Rote -NADH dataset, Subclass 2 | electron microscopy | V | PEE | — |
| 7W2R | Active state CI from DQ-NADH dataset, Subclass 1 | electron microscopy | V | CDL, PEE, PLX | — |
| 7W2U | Active state CI from DQ-NADH dataset, Subclass 2 | electron microscopy | V | CDL, PEE | — |
| 7W2Y | Active state CI from DQ-NADH dataset, Subclass 3 | electron microscopy | V | CDL, PEE, PLX | — |
30 records more on the page itself.
Ligands
- PEE · 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine · in 71 records
- PLX · (9R,11S)-9-({[(1S)-1-hydroxyhexadecyl]oxy}methyl)-2,2-dimethyl-5,7,10-trioxa-2lambda~5~-aza-6lambda~5~-phosphaoctacosane-6,6,11-triol · in 59 records
- CDL · Cardiolipin · in 57 records
- 3PE · 1,2-diacyl-sn-glycero-3-phosphoethanolamine · in 17 records
- PC1 · 1,2-diacyl-sn-glycero-3-phosphocholine · in 10 records
- PGT · (1S)-2-{[{[(2R)-2,3-dihydroxypropyl]oxy}(hydroxy) phosphoryl]oxy}-1-[(palmitoyloxy)methyl]ethyl stearate · in 8 records
- AYA · N-acetylalanine · in 1 record
Elsewhere
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