UniProt H6UQI0
Beta-lactamase (H6UQI0)
Beta-lactamase (UniProt H6UQI0), EC 3.5.2.6: 17 experimental structures on GenesisL1, 10 ligands bound, 3 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- H6UQI0
- Protein
- Beta-lactamase
- EC
- 3.5.2.6
- Experimental structures
- 17
- Predicted models
- 0
- Ligands
- 10
- Pockets
- 3 · 0 records with a druggable one
Structures
17 records of H6UQI0 in the MolNFT archive: 17 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4UA6 | CTX-M-14 Class A Beta-Lactamase Apo Crystal Structure at 0.79 Angstrom Resolution | x-ray diffraction | A, B | — | — |
| 4UA6 | Ctx-M-14 class a beta-lactamase apo crystal structure at 0.79 ångström resolution | x-ray diffraction | A, B | — | — |
| 4UA7 | CTX-M-14 Class A Beta-Lactamase in Complex with a Non-Covalent Inhibitor at Sub-Angstrom Resolution | x-ray diffraction | A, B | — | — |
| 4UA7 | Ctx-M-14 class a beta-lactamase in complex with a non-covalent inhibitor at sub-ångström resolution | x-ray diffraction | A, B | — | — |
| 4UA9 | CTX-M-14 Class A Beta-Lactamase in Complex with a Boronic Acid Acylation Transition State Analog at… | x-ray diffraction | A, B | — | — |
| 4UA9 | Ctx-M-14 class a beta-lactamase in complex with a boronic acid acylation transition state analog at… | x-ray diffraction | A, B | — | — |
| 4UAA | CTX-M-14 Class A Beta-Lactamase in Complex with a Non-Covalent Inhibitor at Sub-Angstrom Resolution | x-ray diffraction | A, B | — | — |
| 4UAA | Ctx-M-14 class a beta-lactamase in complex with a non-covalent inhibitor at sub-ångström resolution | x-ray diffraction | A, B | — | — |
| 5TOP | Atomic resolution X-ray crystal structure of a ruthenocene conjugated beta-lactam antibiotic in… | x-ray diffraction | A, B | K, JSE, JSC, 7G4 | — |
| 5U53 | CTX-M-14 E166A with acylated ceftazidime molecule | x-ray diffraction | A | CAZ, NO3 | 1 (best 0.34) |
| 5U53 | Ctx-M-14 E166A with acylated ceftazidime molecule | x-ray diffraction | A | CAZ, NO3 | — |
| 5VLE | Ultrahigh resolution X-ray crystal structure of ruthenocene conjugated penicilloate and penilloate… | x-ray diffraction | A, B | JSD, JSC, JSE, K, RU, PO4 | — |
| 6MIA | Crystal structure of ctx-M-14 with compound 6 | x-ray diffraction | A, B | 1CE | — |
| 7UON | CTX-M-14 Y105W mutant | x-ray diffraction | A | PO4 | — |
| 8DOE | Crystal Structure of CTX-M-14 N106A | x-ray diffraction | A | — | 1 (best 0.35) |
| 8DON | Beta-lactamase CTX-M-14 T215A | x-ray diffraction | A | PO4 | 1 (best 0.35) |
| 8DP4 | Beta-lactamase CTX-M-14 T235A | x-ray diffraction | A | — | — |
Ligands
- PO4 · Phosphate ion · in 3 records
- CAZ · Acylated ceftazidime · in 2 records
- JSC · [(1,2,3,4,5-eta)-1-(4-{[carboxy(4-carboxy-5,5-dimethyl-1,3-thiazolidin-2-yl)methyl]amino}-4-oxobutanoyl) cyclopentadienyl][(1,2,3,4,5-eta)-cyclopentadienyl]ruthenium · in 2 records
- JSE · [(1,2,3,4,5-eta)-1-(4-{[carboxy(4-carboxy-5,5-dimethyl-1,3-thiazolidin-2-yl)methyl]amino}-4-oxobutanoyl) cyclopentadienyl][(1,2,3,4,5-eta)-cyclopentadienyl]ruthenium · in 2 records
- K · Potassium ion · in 2 records
- NO3 · Nitrate ion · in 2 records
- 1CE · 3-(1H-tetrazol-5-ylmethyl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one · in 1 record
- 7G4 · ruthenocene · in 1 record
- JSD · [(1,2,3,4,5-eta)-1-(4-{[(4-carboxy-5,5-dimethyl-1,3-thiazolidin-2-yl)methyl]amino}-4-oxobutanoyl) cyclopentadienyl][(1,2,3,4,5-eta)-cyclopentadienyl]ruthenium · in 1 record
- RU · Ruthenium ion · in 1 record
Elsewhere
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