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UniProt G3V8S4

Sodium/potassium-transporting ATPase subunit alpha (G3V8S4)

Sodium/potassium-transporting ATPase subunit alpha (UniProt G3V8S4): 2 experimental structures on GenesisL1, 8 ligands bound, 34 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
G3V8S4
Protein
Sodium/potassium-transporting ATPase subunit alpha
Experimental structures
2
Predicted models
0
Ligands
8
Pockets
34 · 2 records with a druggable one

Structures

2 records of G3V8S4 in the MolNFT archive: 2 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
8IJLCyo-EM structure of wildtype non-gastric proton pump in the presence of Na+, AlF and ADPelectron microscopyAALF, MG, ADP, PCW, CLR, NA16 (best 0.71)
8IJMCyo-EM structure of K794A non-gastric proton pump in Na+ bound E1AMPPCP stateelectron microscopyAACP, PCW, CLR, NA18 (best 0.76)

Ligands

  • CLR · Cholesterol · in 2 records
  • NA · Sodium ion · in 2 records
  • PCW · 1,2-dioleoyl-sn-glycero-3-phosphocholine · in 2 records
  • ACP · Phosphomethylphosphonic acid adenylate ester · in 1 record
  • ADP · Adenosine-5'-diphosphate · in 1 record
  • ALF · Tetrafluoroaluminate ion · in 1 record
  • MG · Magnesium ion · in 1 record
  • Q7G · 2-{[(4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranosyl)oxy]methyl}-4-{[(3beta,9beta,14beta, 17beta,25r)-spirost-5-en-3-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranoside · in 1 record

Elsewhere

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