UniProt G0GA88
SthK (G0GA88)
SthK (UniProt G0GA88): 18 experimental structures on GenesisL1, 6 ligands bound, 258 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- G0GA88
- Protein
- SthK
- Experimental structures
- 18
- Predicted models
- 0
- Ligands
- 6
- Pockets
- 258 · 13 records with a druggable one
Structures
18 records of G0GA88 in the MolNFT archive: 18 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6CJQ | Structure of the SthK cyclic nucleotide-gated potassium channel | electron microscopy | A, B, C, D | PGW | 20 (best 0.75) |
| 6CJQ | Structure of the sthk cyclic nucleotide-gated potassium channel | electron microscopy | A, B, C, D | PGW | — |
| 6CJT | Structure of the SthK cyclic nucleotide-gated potassium channel in complex with cGMP | electron microscopy | A, B, C, D | PCG, PGW | 20 (best 0.76) |
| 6CJT | Structure of the sthk cyclic nucleotide-gated potassium channel in complex with cgmp | electron microscopy | A, B, C, D | PCG, PGW | — |
| 6CJU | Structure of the SthK cyclic nucleotide-gated potassium channel in complex with cAMP | electron microscopy | A, B, C, D | CMP, PGW | 20 (best 0.72) |
| 6CJU | Structure of the sthk cyclic nucleotide-gated potassium channel in complex with camp | electron microscopy | A, B, C, D | CMP, PGW | — |
| 6VXZ | SthK P300A cyclic nucleotide-gated potassium channel in the closed state, in complex with cAMP | electron microscopy | A, B, C, D | CMP, PGW | 20 (best 0.71) |
| 6VXZ | Sthk P300A cyclic nucleotide-gated potassium channel in the closed state, in complex with camp | electron microscopy | A, B, C, D | CMP, PGW | — |
| 6VY0 | SthK P300A cyclic nucleotide-gated potassium channel in a putative active state, in complex with… | electron microscopy | A, B, C, D | — | 18 (best 0.73) |
| 6VY0 | Sthk P300A cyclic nucleotide-gated potassium channel in a putative active state, in complex with… | electron microscopy | A, B, C, D | — | — |
| 7RYR | SthK R120A Open State 3 | electron microscopy | A, C, D, B | CMP, PGW | 20 (best 0.75) |
| 7RYS | SthK R120A Open State 2 | electron microscopy | A, B, C, D | CMP, PGW | 20 (best 0.77) |
| 7TJ5 | SthK closed state, cAMP-bound in the presence of POPA | electron microscopy | A, B, C, D | CMP, D21 | 20 (best 0.75) |
| 7TJ6 | SthK open state, cAMP-bound in the presence of POPA | electron microscopy | A, B, C, D | CMP, D21 | 20 (best 0.79) |
| 7TKT | SthK closed state, cAMP-bound in the presence of detergent | electron microscopy | A, B, C, D | CMP, PGW | 20 (best 0.78) |
| 8VT9 | WT SthK in the presence of PIP2 and cAMP | electron microscopy | A, B, C, D | CMP, PT5, PCW | 20 (best 0.75) |
| 8VTA | SthK R120A in the presence of PIP2 and cAMP | electron microscopy | A, B, C, D | CMP, PT5, PCW | 20 (best 0.74) |
| 8VTB | SthK R120A R124A in the presence of PIP2 and cAMP | electron microscopy | A, B, C, D | CMP, PCW | 20 (best 0.75) |
Ligands
- CMP · Adenosine-3',5'-cyclic-monophosphate · in 12 records
- PGW · (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy) phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate · in 11 records
- PCW · 1,2-dioleoyl-sn-glycero-3-phosphocholine · in 3 records
- D21 · (2R)-1-(hexadecanoyloxy)-3-(phosphonooxy)propan-2-yl (9Z)-octadec-9-enoate · in 2 records
- PCG · Cyclic guanosine monophosphate · in 2 records
- PT5 · (1S)-2-{[(R)-hydroxy{[(1r,2r,3s,4r,5r,6s)-2,3,6-trihydroxy-4,5-bis(phosphonooxy) cyclohexyl]oxy}phosphoryl]oxy}-1-[(octadecanoyloxy) methyl]ethyl (8E,11E)-icosa-5,8,11,14-tetraenoate · in 2 records
Elsewhere
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