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UniProt F8VPR5

histone acetyltransferase (F8VPR5)

histone acetyltransferase (UniProt F8VPR5), EC 2.3.1.48: 3 experimental structures on GenesisL1, 3 ligands bound, 16 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
F8VPR5
Protein
histone acetyltransferase
EC
2.3.1.48
Experimental structures
3
Predicted models
0
Ligands
3
Pockets
16 · 2 records with a druggable one

Structures

3 records of F8VPR5 in the MolNFT archive: 3 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
8CMZCrystal structure of CREBBP-R1446C histone acetyltransferase domain in complex with Coenzyme Ax-ray diffractionAZN, COA8 (best 0.71)
8CNBCrystal structure of CREBBP-Y1503C histone acetyltransferase domain in complex with Coenzyme Ax-ray diffractionAZN, COA—
8CNDCrystal structure of CREBBP-Y1482N histone acetyltransferase domain in complex with a bisubstrate…x-ray diffractionAZN, 01K8 (best 0.71)

Ligands

  • ZN · Zinc ion · in 3 records
  • COA · Coenzyme A · in 2 records
  • 01K · [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]methyl (3R,20R)-20-carbamoyl-3-hydroxy-2,2-dimethyl-4,8,14,22-tetraoxo-12-thia-5,9,15,21-tetraazatricos-1-yl dihydrogen diphosphate · in 1 record

Elsewhere

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