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UniProt F6YRW4

Lysine-specific demethylase 2A (F6YRW4)

Lysine-specific demethylase 2A (UniProt F6YRW4), EC 1.14.11.27: 12 experimental structures on GenesisL1, 3 ligands bound, 132 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
F6YRW4
Protein
Lysine-specific demethylase 2A
EC
1.14.11.27
Experimental structures
12
Predicted models
0
Ligands
3
Pockets
132 · 12 records with a druggable one

Structures

12 records of F6YRW4 in the MolNFT archive: 12 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
4QWNHistone demethylase KDM2A-H3K36ME1-alpha-KG complex structurex-ray diffractionA, B, C, DAKG, NI10 (best 0.75)
4QWNHistone demethylase KDM2A-H3K36ME1-alpha-kg complex structurex-ray diffractionA, B, C, DAKG, NI10 (best 0.75)
4QX7Crystal structure of histone demethylase kdm2a-h3k36me2 with alpha-kgx-ray diffractionA, B, C, DAKG, NI9 (best 0.74)
4QX7Crystal structure of histone demethylase KDM2A-H3K36ME2 with alpha-kgx-ray diffractionA, B, C, DAKG, NI9 (best 0.74)
4QX8Crystal structure of histone demethylase kdm2a-h3k36me3 complex with alpha-kgx-ray diffractionA, B, C, DNI, AKG12 (best 0.77)
4QX8Crystal structure of histone demethylase KDM2A-H3K36ME3 complex with alpha-kgx-ray diffractionA, B, C, DNI, AKG12 (best 0.77)
4QXBcrystal structure of histone demethylase KDM2A-H3K36ME3 with NOGx-ray diffractionA, B, C, DOGA, NI13 (best 0.78)
4QXBCrystal structure of histone demethylase KDM2A-H3K36ME3 with nogx-ray diffractionA, B, C, DOGA, NI13 (best 0.78)
4QXCCrystal structure of histone demethylase KDM2A-H3K36ME2 with NOGx-ray diffractionA, B, C, DOGA, NI10 (best 0.79)
4QXCCrystal structure of histone demethylase KDM2A-H3K36ME2 with nogx-ray diffractionA, B, C, DOGA, NI10 (best 0.79)
4QXHCrystal structure of histone demethylase KDM2A-H3K36ME1 with NOGx-ray diffractionA, B, C, DOGA, NI12 (best 0.78)
4QXHCrystal structure of histone demethylase KDM2A-H3K36ME1 with nogx-ray diffractionA, B, C, DOGA, NI12 (best 0.78)

Ligands

  • NI · Nickel (II) ion · in 12 records
  • AKG · 2-oxoglutaric acid · in 6 records
  • OGA · N-oxalylglycine · in 6 records

Elsewhere

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