UniProt F2Z5B2
Tubulin beta chain (F2Z5B2)
Tubulin beta chain (UniProt F2Z5B2): 20 experimental structures on GenesisL1, 9 ligands bound, 232 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- F2Z5B2
- Protein
- Tubulin beta chain
- Experimental structures
- 20
- Predicted models
- 0
- Ligands
- 9
- Pockets
- 232 · 20 records with a druggable one
Structures
20 records of F2Z5B2 in the MolNFT archive: 20 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3J8X | High-resolution structure of no-nucleotide kinesin on microtubules | electron microscopy | B | GTP, GDP | 10 (best 0.83) |
| 3J8X | High-resolution structure of no-nucleotide kinesin on microtubules | electron microscopy | B | GTP, GDP | 10 (best 0.83) |
| 3J8Y | High-resolution structure of ATP analog-bound kinesin on microtubules | electron microscopy | B | GTP, GDP | 9 (best 0.82) |
| 3J8Y | High-resolution structure of ATP analog-bound kinesin on microtubules | electron microscopy | B | GTP, GDP | 9 (best 0.82) |
| 5CA0 | Crystal structure of T2R-TTL-Lexibulin complex | x-ray diffraction | B, D | GTP, MG, GDP, LXL | 14 (best 0.85) |
| 5CA0 | Crystal structure of T2R-ttl-lexibulin complex | x-ray diffraction | B, D | GTP, MG, GDP, LXL | 14 (best 0.85) |
| 5JCB | Microtubule depolymerizing agent podophyllotoxin derivative YJTSF1 | x-ray diffraction | B, D | GTP, MG, GDP, NA, NV4 | 13 (best 0.84) |
| 5JCB | Microtubule depolymerizing agent podophyllotoxin derivative YJTSF1 | x-ray diffraction | B, D | GTP, MG, GDP, NA, NV4 | 13 (best 0.84) |
| 5XKE | Crystal structure of T2R-TTL-Demecolcine complex | x-ray diffraction | B, D | GTP, MG, GDP, LON | 15 (best 0.87) |
| 5XKE | Crystal structure of T2R-ttl-demecolcine complex | x-ray diffraction | B, D | GTP, MG, GDP, LON | 15 (best 0.87) |
| 5XKH | Crystal structure of T2R-TTL-CF1 complex | x-ray diffraction | B, D | GTP, GDP, MG, 89C | 14 (best 0.83) |
| 5XKH | Crystal structure of T2R-ttl-CF1 complex | x-ray diffraction | B, D | GTP, GDP, MG, 89C | 14 (best 0.83) |
| 5XP3 | Crystal structure of apo T2R-TTL | x-ray diffraction | B, D | GTP, MG, GDP | 12 (best 0.82) |
| 5XP3 | Crystal structure of apo T2R-ttl | x-ray diffraction | B, D | GTP, MG, GDP | 12 (best 0.82) |
| 6B0C | KLP10A-AMPPNP in complex with curved tubulin and a microtubule | electron microscopy | B, D | GTP, MG, GDP, TA1 | 12 (best 0.87) |
| 6B0C | KLP10A-amppnp in complex with curved tubulin and a microtubule | electron microscopy | B, D | GTP, MG, GDP, TA1 | 12 (best 0.87) |
| 6B0I | Apo KLP10A in complex with a microtubule | electron microscopy | B | GTP, MG, GDP, TA1 | 8 (best 0.84) |
| 6B0I | Apo KLP10A in complex with a microtubule | electron microscopy | B | GTP, MG, GDP, TA1 | 8 (best 0.84) |
| 6B0L | KLP10A-AMPPNP in complex with a microtubule | electron microscopy | B | GTP, GDP, TA1 | 9 (best 0.87) |
| 6B0L | KLP10A-amppnp in complex with a microtubule | electron microscopy | B | GTP, GDP, TA1 | 9 (best 0.87) |
Ligands
- GDP · Guanosine-5'-diphosphate · in 20 records
- GTP · Guanosine-5'-triphosphate · in 20 records
- MG · Magnesium ion · in 14 records
- TA1 · Taxol · in 6 records
- 89C · 4-[(4-methoxy-3-oxidanyl-phenyl)-methyl-amino]chromen-2-one · in 2 records
- LON · (7S)-1,2,3,10-tetramethoxy-7-(methylamino)-6,7-dihydro-5H-benzo[a]heptalen-9-one · in 2 records
- LXL · 1-ethyl-3-[2-methoxy-4-(5-methyl-4-{[(1S)-1-(pyridin-3-yl)butyl]amino}pyrimidin-2-yl)phenyl]urea · in 2 records
- NA · Sodium ion · in 2 records
- NV4 · (5R,5aR,8aS,9R)-9-[(4H-1,2,4-triazol-3-yl)sulfanyl]-5-(3,4,5-trimethoxyphenyl)-5,8,8a,9-tetrahydro-2H-furo[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(5aH)-one · in 2 records
Elsewhere
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