UniProt F2UB89
TRPM2 chanzyme (F2UB89)
TRPM2 chanzyme (UniProt F2UB89): 13 experimental structures on GenesisL1, 6 ligands bound, 260 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- F2UB89
- Protein
- TRPM2 chanzyme
- Experimental structures
- 13
- Predicted models
- 0
- Ligands
- 6
- Pockets
- 260 · 13 records with a druggable one
Structures
13 records of F2UB89 in the MolNFT archive: 13 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8SR7 | Cryo-EM structure of TRPM2 chanzyme in the presence of Magnesium, Adenosine monophosphate, and… | electron microscopy | A, B, C, D | RP5, AMP, MG, CLR | 20 (best 0.86) |
| 8SR8 | Cryo-EM structure of TRPM2 chanzyme in the presence of EDTA (apo state) | electron microscopy | A, B, C, D | CLR | 20 (best 0.84) |
| 8SR9 | Cryo-EM structure of TRPM2 chanzyme in the presence of Magnesium | electron microscopy | A, B, C, D | MG, CLR | 20 (best 0.84) |
| 8SRB | Cryo-EM structure of TRPM2 chanzyme in the presence of EDTA and ADP-ribose | electron microscopy | A, B, C, D | APR, CLR | 20 (best 0.83) |
| 8SRC | Cryo-EM structure of TRPM2 chanzyme in the presence of Calcium and ADP-ribose | electron microscopy | A, B, C, D | APR, CA, CLR | 20 (best 0.86) |
| 8SRD | Cryo-EM structure of TRPM2 chanzyme in the presence of Magnesium and ADP-ribose, open state | electron microscopy | A, B, C, D | APR, MG, CLR | 20 (best 0.85) |
| 8SRE | Cryo-EM structure of TRPM2 chanzyme in the presence of Magnesium and ADP-ribose, closed state | electron microscopy | A, D, B, C | APR, MG, CLR | 20 (best 0.86) |
| 8SRF | Cryo-EM structure of TRPM2 chanzyme in the presence of Magnesium, ADP-ribose, Adenosine… | electron microscopy | A, B, C, D | RP5, AMP, APR, MG, CLR | 20 (best 0.86) |
| 8SRG | Cryo-EM structure of TRPM2 chanzyme in the presence of Magnesium, Adenosine monophosphate, and… | electron microscopy | A, B, C, D | RP5, AMP, MG, CLR | 20 (best 0.84) |
| 8SRH | Cryo-EM structure of TRPM2 chanzyme (E1114A) in the presence of Magnesium and ADP-ribose, open state | electron microscopy | A, B, C, D | APR, MG, CLR | 20 (best 0.83) |
| 8SRI | Cryo-EM structure of TRPM2 chanzyme (E1114A) in the presence of Magnesium and ADP-ribose, closed… | electron microscopy | A, B, C, D | APR, MG, CLR | 20 (best 0.86) |
| 8SRJ | Cryo-EM structure of TRPM2 chanzyme (without NUDT9-H domain) in the presence of EDTA, apo state | electron microscopy | A, B, C, D | CLR | 20 (best 0.86) |
| 8SRK | Cryo-EM structure of TRPM2 chanzyme (without NUDT9-H domain) in the presence of Ca and ADP-ribose | electron microscopy | A, B, C, D | APR, CA, CLR | 20 (best 0.86) |
Ligands
Elsewhere
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