UniProt F1SIS9

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (F1SIS9)

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (UniProt F1SIS9): 79 experimental structures on GenesisL1, 5 ligands bound, 146 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt: F1SIS9
Protein: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial
Experimental structures: 79
Predicted models: 0
Ligands: 5
Pockets: 146 · 60 records with a druggable one

Structures

79 records of F1SIS9 in the MolNFT archive: 79 experimental, 0 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
5GPN	Architecture of mammalian respirasome	electron microscopy	q, v	—	1 (best 0.81)
5GUP	Cryo-EM structure of mammalian respiratory supercomplex I1III2IV1	electron microscopy	U	CDL	1 (best 0.82)
7V2C	Active state complex I from Q10 dataset	electron microscopy	w	CDL, ADP	2 (best 0.86)
7V2C	Active state complex I from Q10 dataset	electron microscopy	w	CDL, ADP	—
7V2D	Deactive state complex I from Q10 dataset	electron microscopy	w	CDL, ADP	3 (best 0.82)
7V2D	Deactive state complex I from Q10 dataset	electron microscopy	w	CDL, ADP	—
7V2E	Active state complex I from Q10-NADH dataset	electron microscopy	w	CDL, ADP	3 (best 0.83)
7V2E	Active state complex I from Q10-NADH dataset	electron microscopy	w	CDL, ADP	—
7V2F	Deactive state complex I from Q10-NADH dataset	electron microscopy	w	CDL, ADP	3 (best 0.82)
7V2F	Deactive state complex I from Q10-NADH dataset	electron microscopy	w	CDL, ADP	—
7V2H	Active state complex I from DQ-NADH dataset	electron microscopy	w	CDL, ADP	3 (best 0.83)
7V2H	Active state complex I from dq-NADH dataset	electron microscopy	w	CDL, ADP	—
7V2K	Deactive state complex I from DQ-NADH dataset	electron microscopy	w	CDL, ADP	3 (best 0.86)
7V2K	Deactive state complex I from dq-NADH dataset	electron microscopy	w	CDL, ADP	—
7V2R	Active state complex I from Q1-NADH dataset	electron microscopy	w	CDL, ADP	2 (best 0.82)
7V2R	Active state complex I from Q1-NADH dataset	electron microscopy	w	CDL, ADP	—
7V30	Deactive state complex I from Q1-NADH dataset	electron microscopy	w	CDL, ADP	3 (best 0.85)
7V30	Deactive state complex I from Q1-NADH dataset	electron microscopy	w	CDL, ADP	—
7V31	Active state complex I from rote dataset	electron microscopy	w	CDL, ADP	2 (best 0.83)
7V31	Active state complex I from rotenone dataset	electron microscopy	w	CDL, ADP	—
7V32	Deactive state complex I from rotenone dataset	electron microscopy	w	CDL, ADP	—
7V33	Active state complex I from rote -NADH dataset	electron microscopy	w	CDL, ADP	3 (best 0.84)
7V33	Active state complex I from rotenone-NADH dataset	electron microscopy	w	CDL, ADP	—
7V3M	Deactive state complex I from rote -NADH dataset	electron microscopy	w	CDL, ADP	—
7V3M	Deactive state complex I from rotenone-NADH dataset	electron microscopy	w	CDL, ADP	—
7VBL	Membrane arm of active state ci from dq-NADH dataset	electron microscopy	w	CDL, ADP	—
7VBP	Membrane arm of deactive state CI from DQ-NADH dataset	electron microscopy	w	CDL, ADP	—
7VBP	Membrane arm of deactive state ci from dq-NADH dataset	electron microscopy	w	CDL, ADP	—
7VC0	Membrane arm of active state CI from Rote -NADH dataset	electron microscopy	w	CDL, ADP	4 (best 0.82)
7VC0	Membrane arm of active state ci from rotenone-NADH dataset	electron microscopy	w	CDL, ADP	—
7VWL	Membrane arm of deactive state CI from rote -NADH dataset	electron microscopy	w	CDL, ADP	3 (best 0.81)
7VWL	Membrane arm of deactive state ci from rotenone-NADH dataset	electron microscopy	w	CDL, ADP	—
7VXS	Membrane arm of active state CI from Q10 dataset	electron microscopy	w	CDL, ADP	3 (best 0.83)
7VY1	Membrane arm of deactive state CI from Q10 dataset	electron microscopy	w	CDL, ADP	3 (best 0.86)
7VY9	Membrane arm of active state CI from Q10-NADH dataset	electron microscopy	w	CDL, ADP	3 (best 0.83)
7VYE	Membrane arm of deactive state CI from Q10-NADH dataset	electron microscopy	w	CDL, ADP	3 (best 0.83)
7VYS	Membrane arm of active state CI from Q1-NADH dataset	electron microscopy	w	CDL, ADP	3 (best 0.83)
7VZW	Active state CI from Q10 dataset, Subclass 2	electron microscopy	w	CDL, ADP	3 (best 0.83)
7W00	Deactive state CI from Q10 dataset, Subclass 1	electron microscopy	w	CDL, ADP	2 (best 0.86)
7W0H	Deactive state CI from Q10 dataset, Subclass 2	electron microscopy	w	CDL, ADP	3 (best 0.82)
7W0R	Active state CI from Q10-NADH dataset, Subclass 1	electron microscopy	w	CDL, ADP	3 (best 0.86)
7W1O	Deactive state CI from Q10-NADH dataset, Subclass 1	electron microscopy	w	CDL, ADP	4 (best 0.81)
7W1P	Deactive state CI from Q10-NADH dataset, Subclass 2	electron microscopy	w	CDL, ADP	2 (best 0.82)
7W1T	Active state CI from Rote dataset, Subclass 1	electron microscopy	w	CDL, ADP	2 (best 0.84)
7W1U	Active state CI from Rote dataset, Subclass 2	electron microscopy	w	CDL, ADP	1 (best 0.83)
7W1V	Active state CI from Rote -NADH dataset, Subclass 1	electron microscopy	w	CDL, ADP	2 (best 0.83)
7W20	Active state CI from Rote -NADH dataset, Subclass 3	electron microscopy	w	CDL, ADP	3 (best 0.83)
7W2K	Deactive state CI from Rote -NADH dataset, Subclass 1	electron microscopy	w	CDL, ADP	3 (best 0.83)
7W2L	Deactive state CI from Rote -NADH dataset, Subclass 2	electron microscopy	w	CDL, ADP	3 (best 0.84)
7W2R	Active state CI from DQ-NADH dataset, Subclass 1	electron microscopy	w	CDL, ADP	3 (best 0.83)
7W2U	Active state CI from DQ-NADH dataset, Subclass 2	electron microscopy	w	CDL, ADP	3 (best 0.83)
7W2Y	Active state CI from DQ-NADH dataset, Subclass 3	electron microscopy	w	CDL, ADP	3 (best 0.83)
7W31	Deactive state CI from DQ-NADH dataset, Subclass 1	electron microscopy	w	CDL, ADP	3 (best 0.86)
7W32	Deactive state CI from DQ-NADH dataset, Subclass 2	electron microscopy	w	CDL, ADP	3 (best 0.83)
7W35	Deactive state CI from DQ-NADH dataset, Subclass 3	electron microscopy	w	CDL, ADP	2 (best 0.83)
7W4C	Active state CI from Q1-NADH dataset, Subclass 1	electron microscopy	w	CDL, ADP	2 (best 0.83)
7W4E	Active state CI from Q1-NADH dataset, Subclass 3	electron microscopy	w	CDL, ADP	2 (best 0.86)
7W4F	Active state CI from Q1-NADH dataset, Subclass 4	electron microscopy	w	CDL, ADP	2 (best 0.84)
7W4G	Active state CI from Q1-NADH dataset, Subclass 5	electron microscopy	w	CDL, ADP	2 (best 0.83)
7W4J	Deactive state CI from Q1-NADH dataset, Subclass 1	electron microscopy	w	CDL, ADP	—

19 records more on the page itself.

Ligands

CDL · Cardiolipin · in 78 records
ADP · Adenosine-5'-diphosphate · in 60 records
3PE · 1,2-diacyl-sn-glycero-3-phosphoethanolamine · in 17 records
GTP · Guanosine-5'-triphosphate · in 17 records
MG · Magnesium ion · in 17 records

Elsewhere

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.