GL1X · GenesisL1 explorer

UniProt E5RPG3

Genome polyprotein (E5RPG3)

Genome polyprotein (UniProt E5RPG3), EC 2.7.7.48, 3.4.22.28: 11 experimental structures on GenesisL1, 5 ligands bound, 24 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
E5RPG3
Protein
Genome polyprotein
EC
2.7.7.48, 3.4.22.28, 3.4.22.29, 3.6.1.15
Experimental structures
11
Predicted models
0
Ligands
5
Pockets
24 · 5 records with a druggable one

Structures

11 records of E5RPG3 in the MolNFT archive: 11 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
5F8GEnterovirus 71 Polymerase Elongation Complex (C1S1 Form)x-ray diffractionAZN4 (best 0.80)
5F8GEnterovirus 71 polymerase elongation complex (C1S1 form)x-ray diffractionA——
6LSECrystal structure of the enterovirus 71 polymerase elongation complex (C3S6A/C3S6B form)x-ray diffractionAZN, SO4, POP—
6LSECrystal structure of the enterovirus 71 polymerase elongation complex (C3S6A/C3S6B form)x-ray diffractionAZN, SO4, POP—
6LSFCrystal structure of the enterovirus 71 polymerase elongation complex (C2S6RA/C2S6RB form)x-ray diffractionASO4, ZN—
6LSGCrystal structure of the enterovirus 71 polymerase elongation complex (C0S6M form)x-ray diffractionASO4, ZN3 (best 0.83)
6LSGCrystal structure of the enterovirus 71 polymerase elongation complex (C0S6M form)x-ray diffractionASO4, ZN—
6LSHCrystal structure of the enterovirus 71 polymerase elongation complex (C2S6M form)x-ray diffractionASO4, ZN6 (best 0.79)
6LSHCrystal structure of the enterovirus 71 polymerase elongation complex (C2S6M form)x-ray diffractionASO4, ZN—
7W9SCrystal structure of the enterovirus 71 polymerase elongation complex (C1S3 form)x-ray diffractionACTP, SO4, ZN, MG5 (best 0.81)
8XPPCrystal structure of the enterovirus 71 RdRP elongation complex with the nucleoside monophosphate…x-ray diffractionAZN6 (best 0.81)

Ligands

  • ZN · Zinc ion · in 10 records
  • SO4 · Sulfate ion · in 8 records
  • POP · Pyrophosphate 2- · in 2 records
  • CTP · Cytidine-5'-triphosphate · in 1 record
  • MG · Magnesium ion · in 1 record

Elsewhere

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