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UniProt E5RPG2

Genome polyprotein (E5RPG2)

Genome polyprotein (UniProt E5RPG2), EC 2.7.7.48: 12 experimental structures on GenesisL1, 5 ligands bound, 19 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
E5RPG2
Protein
Genome polyprotein
EC
2.7.7.48
Experimental structures
12
Predicted models
0
Ligands
5
Pockets
19 · 4 records with a druggable one

Structures

12 records of E5RPG2 in the MolNFT archive: 12 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
5F8HEnterovirus 71 Polymerase Elongation Complex (C1S1/2 Form)x-ray diffractionASO4, ZN, MG4 (best 0.79)
5F8HEnterovirus 71 polymerase elongation complex (C1S1/2 form)x-ray diffractionA——
5F8IEnterovirus 71 Polymerase Elongation Complex (C1S2/3 Form)x-ray diffractionACTP, ZN, SO4, MG—
5F8IEnterovirus 71 polymerase elongation complex (C1S2/3 form)x-ray diffractionA——
5F8JEnterovirus 71 Polymerase Elongation Complex (C1S4 Form)x-ray diffractionAMG, ZN, SO4, POP5 (best 0.83)
5F8JEnterovirus 71 polymerase elongation complex (C1S4 form)x-ray diffractionA——
5F8LEnterovirus 71 Polymerase Elongation Complex (C3S1 Form)x-ray diffractionAZN—
5F8LEnterovirus 71 polymerase elongation complex (C3S1 form)x-ray diffractionA——
5F8MEnterovirus 71 Polymerase Elongation Complex (C3S4/5 Form)x-ray diffractionAMG, ZN, SO4, POP5 (best 0.80)
5F8MEnterovirus 71 polymerase elongation complex (C3S4/5 form)x-ray diffractionA——
5F8NEnterovirus 71 Polymerase Elongation Complex (C3S6 Form)x-ray diffractionAZN, SO4, POP5 (best 0.80)
5F8NEnterovirus 71 polymerase elongation complex (C3S6 form)x-ray diffractionA——

Ligands

  • ZN · Zinc ion · in 6 records
  • SO4 · Sulfate ion · in 5 records
  • MG · Magnesium ion · in 4 records
  • POP · Pyrophosphate 2- · in 3 records
  • CTP · Cytidine-5'-triphosphate · in 1 record

Elsewhere

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