UniProt E1C3A0
Bestrophin homolog (E1C3A0)
Bestrophin homolog (UniProt E1C3A0): 14 experimental structures on GenesisL1, 3 ligands bound, 40 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- E1C3A0
- Protein
- Bestrophin homolog
- Experimental structures
- 14
- Predicted models
- 0
- Ligands
- 3
- Pockets
- 40 · 2 records with a druggable one
Structures
14 records of E1C3A0 in the MolNFT archive: 14 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4RDQ | Calcium-activated chloride channel bestrophin-1, from chicken, in complex with Fab antibody… | x-ray diffraction | A, B, C, D, E | — | — |
| 4RDQ | Calcium-activated chloride channel bestrophin-1, from chicken, in complex with Fab antibody… | x-ray diffraction | A, B, C, D, E | — | — |
| 5T5N | Calcium-activated chloride channel bestrophin-1 (BEST1), triple mutant: I76A, F80A, F84A; in… | x-ray diffraction | A, B, C, D, E | CL, K, CA | — |
| 6N23 | BEST1 in a calcium-bound inactivated state | electron microscopy | A, B, C, D, E | CA | 20 (best 0.73) |
| 6N23 | BEST1 in a calcium-bound inactivated state | electron microscopy | A, B, C, D, E | CA | — |
| 6N24 | BEST1 open state W287F mutant, calcium-free | electron microscopy | A, B, C, D, E | — | 20 (best 0.77) |
| 6N24 | BEST1 open state W287F mutant, calcium-free | electron microscopy | A, B, C, D, E | — | — |
| 6N25 | BEST1 open state W287F mutant, calcium-bound | electron microscopy | A, B, C, D, E | CA | — |
| 6N26 | BEST1 calcium-free closed state | electron microscopy | A, B, C, D, E | — | — |
| 6N26 | BEST1 calcium-free closed state | electron microscopy | A, B, C, D, E | — | — |
| 6N27 | BEST1 calcium-bound closed state | electron microscopy | A, B, C, D, E | CA | — |
| 6N27 | BEST1 calcium-bound closed state | electron microscopy | A, B, C, D, E | CA | — |
| 6N28 | BEST1 calcium-bound open state | electron microscopy | A, B, C, D, E | CA | — |
| 6N28 | BEST1 calcium-bound open state | electron microscopy | A, B, C, D, E | CA | — |
Ligands
Elsewhere
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