GL1X · GenesisL1 explorer

UniProt E1BF86

Bestrophin (E1BF86)

Bestrophin (UniProt E1BF86): 11 experimental structures on GenesisL1, 4 ligands bound, 100 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
E1BF86
Protein
Bestrophin
Experimental structures
11
Predicted models
0
Ligands
4
Pockets
100 · 5 records with a druggable one

Structures

11 records of E1BF86 in the MolNFT archive: 11 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
6VX5bestrophin-2 Ca2+- unbound state (250 nM Ca2+)electron microscopyE, C, B, A, DCL20 (best 0.79)
6VX5Bestrophin-2 CA2+- unbound state (250 nm CA2+)electron microscopyE, C, B, A, D——
6VX6bestrophin-2 Ca2+-bound state (250 nM Ca2+)electron microscopyE, A, B, C, DCA, CL20 (best 0.79)
6VX6Bestrophin-2 CA2+-bound state (250 nm CA2+)electron microscopyE, A, B, C, DCA—
6VX7bestrophin-2 Ca2+-bound state (5 mM Ca2+)electron microscopyC, A, B, E, DCA, CL20 (best 0.80)
6VX7Bestrophin-2 CA2+-bound state (5 mm CA2+)electron microscopyC, A, B, E, DCA, CL—
6VX8bestrophin-2 Ca2+- unbound state 2 (EGTA only)electron microscopyE, A, B, C, DCL20 (best 0.81)
6VX8Bestrophin-2 CA2+- unbound state 2 (egta only)electron microscopyE, A, B, C, D——
6VX9bestrophin-2 Ca2+- unbound state 1 (EGTA only)electron microscopyA, E, B, C, DCL20 (best 0.81)
6VX9Bestrophin-2 CA2+- unbound state 1 (egta only)electron microscopyA, E, B, C, DCL—
8D1NBBEST2_345 CA2+-bound open stateelectron microscopyE, D, A, C, BCA, MC3, DU0, CL—

Ligands

  • CL · Chloride ion · in 8 records
  • CA · Calcium ion · in 5 records
  • DU0 · 2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R}, 9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4, 8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol · in 1 record
  • MC3 · 1,2-dimyristoyl-rac-glycero-3-phosphocholine · in 1 record

Elsewhere

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