UniProt D9N164
Inward rectifier potassium channel Kirbac3.1 (D9N164)
Inward rectifier potassium channel Kirbac3.1 (UniProt D9N164): 16 experimental structures and 1 predicted model on GenesisL1, 10 ligands bound, 16 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- D9N164
- Protein
- Inward rectifier potassium channel Kirbac3.1
- Experimental structures
- 16
- Predicted models
- 1
- Ligands
- 10
- Pockets
- 16 · 2 records with a druggable one
Structures
17 records of D9N164 in the MolNFT archive: 16 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3ZRS | X-ray crystal structure of a KirBac potassium channel highlights a mechanism of channel opening at… | x-ray diffraction | A | — | — |
| 3ZRS | X-ray crystal structure of a kirbac potassium channel highlights a mechanism of channel opening at… | x-ray diffraction | A | — | — |
| 4LP8 | A Novel Open-State Crystal Structure of the Prokaryotic Inward Rectifier KirBac3.1 | x-ray diffraction | A | — | — |
| 4LP8 | A novel open-state crystal structure of the prokaryotic inward rectifier KIRBAC3.1 | x-ray diffraction | A | — | — |
| 6O9T | KirBac3.1 mutant at a resolution of 4.1 Angstroms | x-ray diffraction | A | K, 6E3 | 1 (best 0.39) |
| 6O9T | KIRBAC3.1 mutant at a resolution of 4.1 ångströms | x-ray diffraction | A | K, 6E3 | — |
| 6O9U | KirBac3.1 at a resolution of 2 Angstroms | x-ray diffraction | A | TMO, K, BA, CL, PCW, Z3P | 2 (best 0.33) |
| 6O9U | KIRBAC3.1 at a resolution of 2 ångströms | x-ray diffraction | A | TMO, K, BA, CL, PCW, Z3P | — |
| 6O9V | KirBac3.1 mutant at a resolution of 3.1 Angstroms | x-ray diffraction | A, B | TMO, K, DDQ, M1M | 5 (best 0.77) |
| 6O9V | KIRBAC3.1 mutant at a resolution of 3.1 ångströms | x-ray diffraction | A, B | TMO, K, DDQ, M1M | — |
| 7ADI | KirBac3.1 W46R: role of a highly conserved tryptophan at the membrane-water interface of Kir channel | x-ray diffraction | A, B | K, MG | 4 (best 0.77) |
| 7ADI | KIRBAC3.1 W46R: role of a highly conserved tryptophan at the membrane- water interface of kir… | x-ray diffraction | A, B | K, MG | — |
| 7N9K | KirBac3.1 L124M mutant | x-ray diffraction | A | PCW, TMO, K | 1 (best 0.34) |
| 7N9K | KIRBAC3.1 L124M mutant | x-ray diffraction | A | PCW, TMO, K | — |
| 7N9L | KirBac3.1 C71S C262S | x-ray diffraction | A | PCW, TMO, K | 1 (best 0.32) |
| 7N9L | KIRBAC3.1 C71S C262S | x-ray diffraction | A | PCW, TMO, K | — |
| D9N164 | AlphaFold monomer V2.0 prediction for inward rectifier potassium channel KIRBAC3.1 (D9N164) | predicted | A | — | 2 (best 0.44) |
Ligands
- K · Potassium ion · in 12 records
- TMO · trimethylamine oxide · in 8 records
- PCW · 1,2-dioleoyl-sn-glycero-3-phosphocholine · in 6 records
- 6E3 · 2,3,5,6-tetramethyl-1H,7H-pyrazolo[1,2-a]pyrazole-1,7-dione · in 2 records
- BA · Barium ion · in 2 records
- CL · Chloride ion · in 2 records
- DDQ · Decylamine-N,N-dimethyl-N-oxide · in 2 records
- M1M · 1,1-Methanediyl Bismethanethiosulfonate · in 2 records
- MG · Magnesium ion · in 2 records
- Z3P · 3,3',3''-phosphoryltripropanoic acid · in 2 records
Experiment against prediction
- 6O9T chain A against the predicted model D9N164: TM-score 0.95, RMSD 1.45 Å
- 6O9T chain A against the predicted model D9N164: TM-score 0.95, RMSD 1.45 Å
- 6O9V chain A against the predicted model D9N164: TM-score 0.95, RMSD 1.30 Å
- 6O9V chain A against the predicted model D9N164: TM-score 0.95, RMSD 1.30 Å
- 6O9V chain B against the predicted model D9N164: TM-score 0.94, RMSD 1.61 Å
- 6O9V chain B against the predicted model D9N164: TM-score 0.94, RMSD 1.61 Å
- 7N9K chain A against the predicted model D9N164: TM-score 0.94, RMSD 1.66 Å
- 7N9K chain A against the predicted model D9N164: TM-score 0.94, RMSD 1.66 Å
- 7ADI chain B against the predicted model D9N164: TM-score 0.93, RMSD 1.47 Å
- 7ADI chain B against the predicted model D9N164: TM-score 0.93, RMSD 1.47 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.