MolNFT v1 · #98961 · protein
A novel open-state crystal structure of the prokaryotic inward rectifier KIRBAC3.1
4LP8 · Inward rectifier potassium channel KIRBAC3.1: “A novel open-state crystal structure of the prokaryotic inward rectifier KIRBAC3.1”. X-ray diffraction, 2 ligands (K, CL), 1 pocket (best druggability 0.39). MolNFT v1 #98961 on…
- PDB
- 4LP8
- Type
- protein
- Length
- 283 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Inward rectifier potassium channel KIRBAC3.1
- UniProt
- D9N164
- Ligands
- K, CL
- Pockets
- 1 · best druggability 0.39
Structure
x-ray diffraction · 1 distinct chain · 29% helix, 33% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Inward rectifier potassium channel KIRBAC3.1 | protein | 283 | 29% helix, 33% strand | D9N164 |
Ligands and binding sites
- K · Potassium ion · metal · 8 copies · chains A
- CL · Chloride ion · ion · 3 copies · chains A
- PEG · Di(hydroxyethyl)ether · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 80 | 0.39 | 0.77 | 14 | PEG |
Compared structures
- 4LP8 · A Novel Open-State Crystal Structure of the Prokaryotic Inward Rectifier KirBac3.1 · the same entry in another collection · chain A against A, TM-score 1.00
- D9N164 · AlphaFold monomer V2.0 prediction for inward rectifier potassium channel KIRBAC3.1… · a predicted model of the same protein · chain A against A, TM-score 0.92
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt D9N164
- Elsewhere: RCSB PDB 4LP8 · PDBe 4LP8 · UniProt D9N164
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