UniProt D3ZK93

Glutamate receptor 2,Germ cell-specific gene 1-like protein (D3ZK93)

Glutamate receptor 2,Germ cell-specific gene 1-like protein (UniProt D3ZK93): 8 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 60 pockets. Binding sites, druggability and experiment against…

UniProt: D3ZK93
Protein: Glutamate receptor 2,Germ cell-specific gene 1-like protein
Experimental structures: 8
Predicted models: 1
Ligands: 3
Pockets: 60 · 3 records with a druggable one

Structures

9 records of D3ZK93 in the MolNFT archive: 8 experimental, 1 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
5VHW	GluA2-0xGSG1L bound to ZK	electron microscopy	A, B, C, D	ZK1, NAG	20 (best 0.86)
5VHW	GLUA2-0XGSG1L bound to zk	electron microscopy	A, B, C, D	ZK1, NAG	—
5VHX	GluA2-1xGSG1L bound to ZK	electron microscopy	A, B, C, D, E	ZK1, NAG	20 (best 0.85)
5VHX	GLUA2-1XGSG1L bound to zk	electron microscopy	A, B, C, D, E	ZK1, NAG	—
5VHY	GluA2-2xGSG1L bound to ZK	electron microscopy	A, B, C, D, E, F	ZK1, NAG	20 (best 0.85)
5VHY	GLUA2-2XGSG1L bound to zk	electron microscopy	A, B, C, D, E, F	ZK1, NAG	—
5VHZ	GluA2-2xGSG1L bound to L-Quisqualate	electron microscopy	A, B, C, D, E, F	QUS	—
5VHZ	GLUA2-2XGSG1L bound to L-quisqualate	electron microscopy	A, B, C, D, E, F	QUS	—
D3ZK93	AlphaFold monomer V2.0 prediction for germ cell-specific gene 1-like protein (D3ZK93)	predicted	A	—	—

Ligands

NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 6 records
ZK1 · {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid · in 6 records
QUS · (S)-2-amino-3-(3,5-dioxo-[1,2,4]oxadiazolidin-2-yl)-propionic acid · in 2 records

Experiment against prediction

5VHY chain E against the predicted model D3ZK93: TM-score 0.91, RMSD 1.75 Å
5VHY chain E against the predicted model D3ZK93: TM-score 0.91, RMSD 1.75 Å
5VHX chain E against the predicted model D3ZK93: TM-score 0.90, RMSD 1.76 Å
5VHX chain E against the predicted model D3ZK93: TM-score 0.90, RMSD 1.76 Å
5VHY chain F against the predicted model D3ZK93: TM-score 0.90, RMSD 1.78 Å
5VHZ chain E against the predicted model D3ZK93: TM-score 0.90, RMSD 1.78 Å
5VHZ chain E against the predicted model D3ZK93: TM-score 0.90, RMSD 1.78 Å
5VHX chain A against the predicted model P19491: TM-score 0.85, RMSD 3.60 Å
5VHW chain A against the predicted model P19491: TM-score 0.85, RMSD 3.60 Å
5VHY chain A against the predicted model P19491: TM-score 0.85, RMSD 3.60 Å

Elsewhere

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