UniProt C7Z7K1
Lipid scramblase nhTMEM16 (C7Z7K1)
Lipid scramblase nhTMEM16 (UniProt C7Z7K1): 29 experimental structures on GenesisL1, 2 ligands bound, 289 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- C7Z7K1
- Protein
- Lipid scramblase nhTMEM16
- Experimental structures
- 29
- Predicted models
- 0
- Ligands
- 2
- Pockets
- 289 · 18 records with a druggable one
Structures
29 records of C7Z7K1 in the MolNFT archive: 29 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4WIS | Crystal structure of the lipid scramblase nhTMEM16 in crystal form 1 | x-ray diffraction | A, B | — | — |
| 4WIS | Crystal structure of the lipid scramblase NHTMEM16 in crystal form 1 | x-ray diffraction | A, B | — | — |
| 4WIT | TMEM16 lipid scramblase in crystal form 2 | x-ray diffraction | A, B | — | — |
| 4WIT | TMEM16 lipid scramblase in crystal form 2 | x-ray diffraction | A, B | — | — |
| 6OY3 | nhTMEM16 L302A +Ca2+ in nanodiscs | electron microscopy | B, A | CA | 19 (best 0.76) |
| 6OY3 | NHTMEM16 L302A +CA2+ in nanodiscs | electron microscopy | B, A | CA | — |
| 6QM4 | Cryo-EM structure of calcium-free nhTMEM16 lipid scramblase in nanodisc | electron microscopy | A, B | — | 18 (best 0.80) |
| 6QM4 | Cryo-EM structure of calcium-free NHTMEM16 lipid scramblase in nanodisc | electron microscopy | A, B | — | — |
| 6QM5 | Cryo-EM structure of calcium-bound nhTMEM16 lipid scramblase in DDM | electron microscopy | A, B | CA | 20 (best 0.81) |
| 6QM5 | Cryo-EM structure of calcium-bound NHTMEM16 lipid scramblase in ddm | electron microscopy | A, B | CA | — |
| 6QM6 | Cryo-EM structure of calcium-free nhTMEM16 lipid scramblase in DDM | electron microscopy | A, B | — | 20 (best 0.76) |
| 6QM6 | Cryo-EM structure of calcium-free NHTMEM16 lipid scramblase in ddm | electron microscopy | A, B | — | — |
| 6QM9 | Cryo-EM structure of calcium-bound nhTMEM16 lipid scramblase in nanodisc (open state) | electron microscopy | A, B | CA | 20 (best 0.78) |
| 6QM9 | Cryo-EM structure of calcium-bound NHTMEM16 lipid scramblase in nanodisc (open state) | electron microscopy | A, B | CA | — |
| 6QMA | Cryo-EM structure of calcium-bound nhTMEM16 lipid scramblase in nanodisc (intermediate state) | electron microscopy | A, B | CA | 20 (best 0.79) |
| 6QMA | Cryo-EM structure of calcium-bound NHTMEM16 lipid scramblase in nanodisc (intermediate state) | electron microscopy | A, B | CA | — |
| 6QMB | Cryo-EM structure of calcium-bound nhTMEM16 lipid scramblase in nanodisc (closed state) | electron microscopy | A, B | CA | 17 (best 0.79) |
| 6QMB | Cryo-EM structure of calcium-bound NHTMEM16 lipid scramblase in nanodisc (closed state) | electron microscopy | A, B | CA | — |
| 8TOI | nhTMEM16 lipid scramblase in lipid nanodiscs with MSP1E3 scaffold protein in the presence of Ca2+… | electron microscopy | A, B | CA, PGW | 20 (best 0.78) |
| 8TOK | nhTMEM16 lipid scramblase in lipid nanodiscs with MSP2N2 scaffold protein in the presence of Ca2+… | electron microscopy | A, B | CA | 17 (best 0.73) |
| 8TOL | nhTMEM16 lipid scramblase in lipid nanodiscs with MSP1E3 scaffold protein in the presence of Ca2+… | electron microscopy | A, B | CA, PGW | 20 (best 0.73) |
| 8TPM | nhTMEM16 lipid scramblase in lipid nanodiscs with MSP1E3 scaffold protein in the absence of Ca2+ | electron microscopy | B, A | PGW | 20 (best 0.79) |
| 8TPN | nhTMEM16 lipid scramblase in lipid nanodiscs with MSP2N2 scaffold protein in the presence of Ca2+… | electron microscopy | A, B | CA | 12 (best 0.79) |
| 8TPO | nhTMEM16 R432A mutant in lipid nanodiscs with MSP1E3 scaffold protein in the presence of Ca2+ | electron microscopy | B, A | CA, PGW | 15 (best 0.78) |
| 8TPP | nhTMEM16 R432A mutant in lipid nanodiscs with MSP2N2 scaffold protein in the presence of Ca2+ | electron microscopy | A, B | CA | 12 (best 0.77) |
| 8TPQ | nhTMEM16 A444P mutant in lipid nanodiscs with MSP1E3 scaffold protein in the presence of Ca2+ (long… | electron microscopy | A, B | CA, PGW | 10 (best 0.75) |
| 8TPR | nhTMEM16 A444P mutant in lipid nanodiscs with MSP1E3 scaffold protein in the presence of Ca2+… | electron microscopy | A, B | CA, PGW | 9 (best 0.78) |
| 8TPS | nhTMEM16 A444P mutant in lipid nanodiscs with MSP1E3 scaffold protein in the presence of Ca2+ (bent… | electron microscopy | A, B | CA, PGW | 8 (best 0.78) |
| 8TPT | nhTMEM16 A444P mutant in lipid nanodiscs with MSP1E3 scaffold protein in the presence of Ca2+ (long… | electron microscopy | A, B | CA, PGW | 12 (best 0.76) |
Ligands
Elsewhere
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