UniProt B8XX90
Stimulator of interferon genes protein (B8XX90)
Stimulator of interferon genes protein (UniProt B8XX90): 10 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 8 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- B8XX90
- Protein
- Stimulator of interferon genes protein
- Experimental structures
- 10
- Predicted models
- 1
- Ligands
- 5
- Pockets
- 8 · 4 records with a druggable one
Structures
11 records of B8XX90 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6A03 | Structure of pSTING complex | x-ray diffraction | A, B | SO4, 2BA | 1 (best 0.83) |
| 6A03 | Structure of psting complex | x-ray diffraction | A, B | SO4, 2BA | — |
| 6A04 | Structure of pSTING complex | x-ray diffraction | A, B | SO4, C2E | 1 (best 0.79) |
| 6A04 | Structure of psting complex | x-ray diffraction | A, B | SO4, C2E | — |
| 6A05 | Structure of pSTING complex | x-ray diffraction | A, B | SO4, 1YD | 2 (best 0.80) |
| 6A05 | Structure of psting complex | x-ray diffraction | A, B | SO4, 1YD | — |
| 6A06 | Structure of pSTING complex | x-ray diffraction | A, B | SO4, 1SY | 1 (best 0.79) |
| 6A06 | Structure of psting complex | x-ray diffraction | A, B | SO4, 1SY | — |
| 6IYF | Structure of pSTING complex | x-ray diffraction | A, B | SO4, 2BA | — |
| 6IYF | Structure of psting complex | x-ray diffraction | A, B | SO4, 2BA | — |
| B8XX90 | AlphaFold monomer V2.0 prediction for stimulator of interferon genes protein (B8XX90) | predicted | A | — | 3 (best 0.49) |
Ligands
- SO4 · Sulfate ion · in 10 records
- 2BA · (2r,3r,3as,5r,7ar,9r,10r,10as,12r,14ar)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-D:3', 2'-J][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5, 10,12-tetrol 5,12-dioxide · in 4 records
- 1SY · cGAMP · in 2 records
- 1YD · 2-amino-9-[(2r,3r,3ar,5s,7as,9r,10r,10ar,12r,14as)-9-(6-amino-9H-purin-9-yl)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-D:3',2'-J][1,3,7,9, 2,8]tetraoxadiphosphacyclododecin-2-yl]-1,9-dihydro-6H-purin-6-one · in 2 records
- C2E · 9,9'-[(2r,3r,3as,5s,7ar,9r,10r,10as,12s,14ar)-3,5,10, 12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3, 2-D:3',2'-J][1,3,7,9,2, 8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one) · in 2 records
Experiment against prediction
- 6A03 chain A against the predicted model B8XX90: TM-score 0.98, RMSD 0.76 Å
- 6A03 chain A against the predicted model B8XX90: TM-score 0.98, RMSD 0.76 Å
- 6A03 chain B against the predicted model B8XX90: TM-score 0.97, RMSD 0.95 Å
- 6A03 chain B against the predicted model B8XX90: TM-score 0.97, RMSD 0.95 Å
- 6A05 chain B against the predicted model B8XX90: TM-score 0.94, RMSD 1.34 Å
- 6A05 chain B against the predicted model B8XX90: TM-score 0.94, RMSD 1.34 Å
- 6A05 chain A against the predicted model B8XX90: TM-score 0.94, RMSD 1.33 Å
- 6A05 chain A against the predicted model B8XX90: TM-score 0.94, RMSD 1.33 Å
- 6A06 chain A against the predicted model B8XX90: TM-score 0.94, RMSD 1.27 Å
- 6A06 chain A against the predicted model B8XX90: TM-score 0.94, RMSD 1.27 Å
Elsewhere
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