UniProt B2R6A7
Glucosylceramidase (B2R6A7)
Glucosylceramidase (UniProt B2R6A7), EC 3.2.1.45: 8 experimental structures on GenesisL1, 6 ligands bound, 28 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- B2R6A7
- Protein
- Glucosylceramidase
- EC
- 3.2.1.45
- Experimental structures
- 8
- Predicted models
- 0
- Ligands
- 6
- Pockets
- 28 · 3 records with a druggable one
Structures
8 records of B2R6A7 in the MolNFT archive: 8 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2WCG | X-ray structure of acid-beta-glucosidase with N-octyl(cyclic guanidine)-nojirimycin in the active… | x-ray diffraction | A, B | — | — |
| 2WCG | X-ray structure of acid-beta-glucosidase with N-OCTYL(CYCLIC guanidine)-nojirimycin in the active… | x-ray diffraction | A, B | — | — |
| 6Q1N | Glucocerebrosidase in complex with pharmacological chaperone IMX8 | x-ray diffraction | A, B | NAG, SO4, P9V | 6 (best 0.71) |
| 6Q1N | Glucocerebrosidase in complex with pharmacological chaperone IMX8 | x-ray diffraction | A, B | NAG, SO4, P9V | — |
| 6Q1P | Glucocerebrosidase in complex with pharmacological chaperone norIMX8 | x-ray diffraction | A, B | NAG, SO4, P8Y | 6 (best 0.65) |
| 6Q1P | Glucocerebrosidase in complex with pharmacological chaperone NORIMX8 | x-ray diffraction | A, B | NAG, SO4, P8Y | — |
| 6T13 | Crystal structure of glucocerebrosidase in complex with a pyrrolopyrazine | x-ray diffraction | A, B, C, D | NAG, SO4, M7H, CL | 16 (best 0.87) |
| 6T13 | Crystal structure of glucocerebrosidase in complex with a pyrrolopyrazine | x-ray diffraction | A, B, C, D | NAG, SO4, M7H, CL | — |
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 6 records
- SO4 · Sulfate ion · in 6 records
- CL · Chloride ion · in 2 records
- M7H · 1-[4-[2-(4-methoxyphenyl)-5-methyl-pyrrolo[2,3-b]pyrazin-6-yl]piperidin-1-yl]ethanone · in 2 records
- P8Y · (2S,3S,4S,5R)-2-{[(4-methylpentyl) sulfonyl]methyl}piperidine-3,4,5-triol · in 2 records
- P9V · (2R,3S,4S,5R)-2-[2-(methylsulfanyl)ethyl]piperidine-3, 4,5-triol · in 2 records
Elsewhere
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