MolNFT v1 · #161034 · protein
Glucocerebrosidase in complex with pharmacological chaperone IMX8
6Q1N: “Glucocerebrosidase in complex with pharmacological chaperone IMX8”. X-ray diffraction, 5 ligands (P9V, NAG, FUC). MolNFT v1 #161034 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6Q1N
- Type
- protein
- Length
- 983 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- B2R6A7
- Ligands
- P9V, NAG, FUC, MAN, SO4
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 489 | — | B2R6A7 |
| B | — | protein | 494 | — | B2R6A7 |
Ligands and binding sites
- P9V · (2R,3S,4S,5R)-2-[2-(methylsulfanyl)ethyl]piperidine-3, 4,5-triol · ligand · 2 copies · chains A, B
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 7 copies · chains A, B
- FUC · alpha-L-fucopyranose · sugar
- MAN · alpha-D-mannopyranose · sugar
- SO4 · Sulfate ion · ion · 17 copies · chains A, B
- EDO · 1,2-ethanediol · additive · 16 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6Q1N · Glucocerebrosidase in complex with pharmacological chaperone IMX8 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt B2R6A7
- Elsewhere: RCSB PDB 6Q1N · PDBe 6Q1N · UniProt B2R6A7
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