UniProt A8PWE4

Asparaginyl-tRNA synthetase, cytoplasmic (A8PWE4)

Asparaginyl-tRNA synthetase, cytoplasmic (UniProt A8PWE4), EC 6.1.1.4: 4 experimental structures on GenesisL1, 5 ligands bound, 26 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt: A8PWE4
Protein: Asparaginyl-tRNA synthetase, cytoplasmic
EC: 6.1.1.4
Experimental structures: 4
Predicted models: 0
Ligands: 5
Pockets: 26 · 2 records with a druggable one

Structures

4 records of A8PWE4 in the MolNFT archive: 4 experimental, 0 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
2XGT	Asparaginyl-tRNA synthetase from Brugia malayi complexed with the sulphamoyl analogue of…	x-ray diffraction	A, B	NSS, MG	13 (best 0.82)
2XGT	Asparaginyl-tRNA synthetase from brugia malayi complexed with the sulphamoyl analogue of…	x-ray diffraction	A, B	—	—
2XTI	Asparaginyl-tRNA synthetase from Brugia malayi complexed with ATP:Mg and L-Asp-beta-NOH…	x-ray diffraction	A, B	NB8, POP, MG, ATP	13 (best 0.82)
2XTI	Asparaginyl-tRNA synthetase from brugia malayi complexed with ATP:MG and L-asp-beta-noh…	x-ray diffraction	A, B	—	—

Ligands

MG · Magnesium ion · in 2 records
ATP · Adenosine-5'-triphosphate · in 1 record
NB8 · 5'-O-[(R)-{[(2S)-2-amino-4-(hydroxyamino)-4-oxobutanoyl]oxy}(hydroxy)phosphoryl]adenosine · in 1 record
NSS · 5'-O-[N-(L-asparaginyl)sulfamoyl]adenosine · in 1 record
POP · Pyrophosphate 2- · in 1 record

Elsewhere

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