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UniProt A7T1N0

Transient receptor potential cation channel subfamily M member-like 2 (A7T1N0)

Transient receptor potential cation channel subfamily M member-like 2 (UniProt A7T1N0): 4 experimental structures on GenesisL1, 5 ligands bound, 20 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
A7T1N0
Protein
Transient receptor potential cation channel subfamily M member-like 2
Experimental structures
4
Predicted models
0
Ligands
5
Pockets
20 · 1 record with a druggable one

Structures

4 records of A7T1N0 in the MolNFT archive: 4 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
6CO7Structure of the nvTRPM2 channel in complex with Ca2+electron microscopyA, B, C, DNAG, CLR, POV, CA—
6CO7Structure of the NVTRPM2 channel in complex with CA2+electron microscopyA, B, C, DNAG, CLR, POV, CA—
9JJENematostella vectensis TRPM2 tetramer in complex with ADPRP/Ca2+electron microscopyA, B, C, DNAG, CA, A2R20 (best 0.86)
A7T1N0AlphaFold monomer V2.0 prediction for transient receptor potential cation channel subfamily M…———

Ligands

  • CA · Calcium ion · in 3 records
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 3 records
  • CLR · Cholesterol · in 2 records
  • POV · (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate · in 2 records
  • A2R · [(2R,3R,4R,5R)-5-(6-amino-9H-purin-9-yl)-3-hydroxy-4-(phosphonooxy)tetrahydrofuran-2-yl]methyl [(2R,3S,4R,5R)-3,4,5-trihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate · in 1 record

Elsewhere

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