UniProt A6XGL2
Insulin (A6XGL2)
Insulin (UniProt A6XGL2): 14 experimental structures on GenesisL1, 29 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- A6XGL2
- Protein
- Insulin
- Experimental structures
- 14
- Predicted models
- 0
- Pockets
- 29 · 5 records with a druggable one
Structures
14 records of A6XGL2 in the MolNFT archive: 14 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2W44 | Structure DeltaA1-A4 insulin | x-ray diffraction | A, B, C, D, E, F | — | — |
| 2W44 | Structure DELTAA1-A4 insulin | x-ray diffraction | A, B, C, D, E, F | — | — |
| 5WDM | An ultra-stable single-chain insulin analog resists thermal inactivation and exhibits biological… | x-ray diffraction | A, B, C, D, E, F | — | 5 (best 0.60) |
| 5WDM | An ultra-stable single-chain insulin analog resists thermal inactivation and exhibits biological… | x-ray diffraction | A, B, C, D, E, F | — | — |
| 6PXV | Cryo-EM structure of full-length insulin receptor bound to 4 insulin. 3D refinement was focused on… | electron microscopy | D, E, F, G | — | 5 (best 0.77) |
| 6PXV | Cryo-EM structure of full-length insulin receptor bound to 4 insulin. 3D refinement was focused on… | electron microscopy | D, E, F, G | — | — |
| 6PXW | Cryo-EM structure of full-length insulin receptor bound to 4 insulin. 3D refinement was focused on… | electron microscopy | C, D, E, F | — | 8 (best 0.78) |
| 6PXW | Cryo-EM structure of full-length insulin receptor bound to 4 insulin. 3D refinement was focused on… | electron microscopy | C, D, E, F | — | — |
| 7BW7 | Cryo-EM Structure for the Ectodomain of the Full-length Human Insulin Receptor in Complex with 1… | electron microscopy | D | — | 5 (best 0.83) |
| 7BW7 | Cryo-EM structure for the ectodomain of the full-length human insulin receptor in complex with 1… | electron microscopy | D | — | — |
| 7BW8 | Cryo-EM Structure for the Insulin Binding Region in the Ectodomain of the Full-length Human Insulin… | electron microscopy | D | — | — |
| 7BW8 | Cryo-EM structure for the insulin binding region in the ectodomain of the full-length human insulin… | electron microscopy | D | — | — |
| 7BWA | Cryo-EM Structure for the Ectodomain of the Full-length Human Insulin Receptor in Complex with 2… | electron microscopy | D, E | — | 6 (best 0.78) |
| 7BWA | Cryo-EM structure for the ectodomain of the full-length human insulin receptor in complex with 2… | electron microscopy | D, E | — | — |
Experiment against prediction
- 7BW7 chain D against the predicted model P01308: TM-score 0.32, RMSD 3.90 Å
- 7BW8 chain D against the predicted model P01308: TM-score 0.32, RMSD 3.87 Å
- 7BWA chain E against the predicted model P01308: TM-score 0.30, RMSD 3.86 Å
- 7BWA chain D against the predicted model P01308: TM-score 0.30, RMSD 3.86 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.